DPBRN Prevalence of Questionable Occlusal Caries Lesions

This study has been completed.
HealthPartners Institute
Kaiser Permanente
Permanente Dental Associates Group, Oregon
National Institute of Dental and Craniofacial Research (NIDCR)
Information provided by:
Dental Practice-Based Research Network
ClinicalTrials.gov Identifier:
First received: September 13, 2010
Last updated: March 3, 2011
Last verified: March 2011
The purpose of this study was to investigate the process involved when making decisions about the diagnosis and treatment of questionable lesions, as well as determine if there is any association between lesions progression (or depth, if opened) and clinical characteristics and baseline risk assessment.

Dental Caries

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Prevalence of Questionable Occlusal Caries Lesions

Resource links provided by NLM:

Further study details as provided by Dental Practice-Based Research Network:

Estimated Enrollment: 2624
Study Start Date: August 2008
Study Completion Date: March 2010
Primary Completion Date: March 2010 (Final data collection date for primary outcome measure)
Questionable occlusal lesions

Detailed Description:

The term"questionable" is defined as a tooth with no cavitation (no continuity break in the enamel) and no radiographic radiolucencies, but the presence of caries is suspected due to roughness, surface opacities, or staining. The characteristics of these lesions and the patient's baseline caries risk were examined.

There have been very few studies regarding questionable lesions, virtually no clinical evaluations of the progression of questionable lesions over time, and no studies depicting the prevalence of these lesions. Since carious lesions have the ability to arrest and possibly reverse, determining how often these lesions are being seen in practice and learning more about their characteristics and patient risk assessment are important steps in order to manage these lesions without unnecessary surgical intervention.


Ages Eligible for Study:   6 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
The participants directly involved in this study were the patients who have sought dental treatment in the DPBRN practitioner-investigators' practices.

Inclusion Criteria:

  • patients needed to have at least one permanent tooth with a questionable lesion. This means that subjects were at least 6 years old because that is when the permanent first molar typically erupts.

Exclusion Criteria:

  • patients under 6 years old
  • patients 6 years old and older who do not have a questionable lesion
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01201447

United States, Alabama
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, Florida
University of Florida College of Dentistry
Gainesville, Florida, United States, 32610
United States, Minnesota
Health Partners Dental Group
Minneapolis, Minnesota, United States, 55440-1309
Health Partners Research Foundation
Minneapolis, Minnesota, United States, 55440-1524
United States, Oregon
Kaiser Permanente Center for Health Research
Portland, Oregon, United States, 97227
Permanente Denrtal Associates
Portland, Oregon, United States, 97232
University of Copenhagen Royal Dental College
Copenhagen, Denmark
Sponsors and Collaborators
Dental Practice-Based Research Network
HealthPartners Institute
Kaiser Permanente
Permanente Dental Associates Group, Oregon
National Institute of Dental and Craniofacial Research (NIDCR)
Principal Investigator: Sonia K Makhija, DDS, MPH University of Alabama at Birmingham
  More Information

Additional Information:
No publications provided

Responsible Party: Gregg H. Gilbert, DDS MBA, Study Chair, University of Alabama at Birmingahm
ClinicalTrials.gov Identifier: NCT01201447     History of Changes
Other Study ID Numbers: 119275, U01DE016747
Study First Received: September 13, 2010
Last Updated: March 3, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Dental Practice-Based Research Network:
Questionable Caries

Additional relevant MeSH terms:
Dental Caries
Stomatognathic Diseases
Tooth Demineralization
Tooth Diseases

ClinicalTrials.gov processed this record on November 30, 2015