Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2010 by Nova Scotia Health Authority.
Recruitment status was  Not yet recruiting
Information provided by:
Nova Scotia Health Authority
ClinicalTrials.gov Identifier:
First received: September 10, 2010
Last updated: NA
Last verified: September 2010
History: No changes posted
Dysphagia is a common reason for referal to the investigators Gastoenterology service. As many as 14% of patients undergoing radiological studies for dysphagia are found to have schatzki rings. Current recommendations for treatment of patients with symptomatic Schatzki rings are based on ancedotal experience and uncontrolled studies. The only randomized study on comparison of techniques the investigators were able to locate was published in 2000 and included only 26 patients. This study demonstrated that the biopsy techinque was as effective as and better tolerated than the standard dilation technique. Considering that the cost and time required for dilatation is greater than the basic biopsy technique, significant cost savings could be achieved using the biopsy technique. As well, patient satisfaction is an important factor considering that Schatzki rings can recur and repeated endoscopy is often required. Therefore, a study that shows a technique to be as or better than the current standard in effectiveness, cost, time, and patient comfort could lead to shift in current practice.

Condition Intervention
Schatzki Ring
Procedure: Biopsy
Procedure: Dilation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation

Further study details as provided by Nova Scotia Health Authority:

Primary Outcome Measures:
  • Effectiveness of biopsy vs dilation

Arms Assigned Interventions
Active Comparator: Biopsy Arm Procedure: Biopsy
Active Comparator: Dilation Arm Procedure: Dilation


Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Presenting to endoscopy unit with symptoms of dysphagia or known history of schatzki ring

Exclusion Criteria:

  • Prior esophageal or gastric surgery, severe esophagitis, coagulopathy
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01200147

Contact: Michael Curley, MD, FRCPC 9024043511 ma_curley@hotmail.com

Canada, Nova Scotia
VG Hospital-Capital District Health Authority Not yet recruiting
Halifax, Nova Scotia, Canada, B3H2Y9
Contact: Michael Curley, MD, FRCPC    9024043511    ma_curley@hotmail.com   
Contact: Mark MacMillan, MD, FRCPC    9024732222    mamacmil@dal.ca   
Sponsors and Collaborators
Nova Scotia Health Authority
  More Information

Responsible Party: Dr. Michael Curley, Division of Gastroenterology, Department of Medicine
ClinicalTrials.gov Identifier: NCT01200147     History of Changes
Other Study ID Numbers: Schatzki-2010 
Study First Received: September 10, 2010
Last Updated: September 10, 2010
Health Authority: Canada: Capital Heath Research Ethics Board

ClinicalTrials.gov processed this record on May 04, 2016