POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia
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|ClinicalTrials.gov Identifier: NCT01199913|
Recruitment Status : Completed
First Posted : September 13, 2010
Last Update Posted : September 9, 2014
|Condition or disease||Intervention/treatment|
|1. Postoperative Cognitive Dysfunction||Other: The intervention will be Mini-Mental Status Examination (MMSE)|
|Study Type :||Observational|
|Actual Enrollment :||110 participants|
|Observational Model:||Case Control|
|Official Title:||Incidence of Postoperative Cognitive Dysfunction in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia: A Randomized, Controlled Trial|
|Study Start Date :||August 2010|
|Primary Completion Date :||August 2014|
|Study Completion Date :||August 2014|
desflurane and sevoflurane
Subjects will be randomized to either desflurane or sevoflurane. They will be given the Mini Mental State exam at 1, 6 and 24 hours after the end of anesthesia.
Other: The intervention will be Mini-Mental Status Examination (MMSE)
A questionnaire given to the study patient before and after the anesthetic at 1, 6 and 24 hours.
- POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia [ Time Frame: Both groups will complete the MMSE at 1, 6, and 24 hours after the end of anesthesia or to disharge up to 7 days. ]The primary outcome measure will be changes in cognitive function after anesthesia as measured by MMSE.
- Secondary outcome measures will include: 1) time to extubation, anesthetic complications (e.g. coughing during extubation), 2) time to readiness for discharge from PACU, 3) length of hospital stay, and 4) any postoperative complications. [ Time Frame: 24 hours to 7 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01199913
|United States, California|
|Loma Linda University|
|Loma Linda, California, United States, 92354|