Clinical Research Center for Dementia of South Korea (CREDOS)(or CRCD) (CREDOS)
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ClinicalTrials.gov Identifier: NCT01198093
Verified September 2012 by Doh Kwan Kim, Samsung Medical Center. Recruitment status was: Recruiting
The objective of this study is to present evidence-based medicine for development of clinical practice guideline through prospective study of Alzheimer's disease(AD) and mild cognitive impairment(MCI) in korea
Condition or disease
The specific aims of this study is (1) construction & maintenance of cohort for Alzheimer's disease(AD) and mild cognitive impairment(MCI); (2) study of epidemiology, rate of progression, risk factor, prognostic factor; (3) study of biomarker such as neuropsychological assessment, peripheral & CSF markers, neuroimaging(both structural & functional)
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Ages Eligible for Study:
Child, Adult, Senior
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patient populatin who is suffering from memory impairment
Normal subjects matched with age and gender
Alzheimer's disease(AD) and mild cognitive impairment(MCI)will be enrolled in the study.
the diagnostic criteria of Alzheimer's disease(AD) according to DSM IV or NINCDS -ADRDA
the diagnostic criteria of mild cognitive impairment(MCI) A. Memory or other cognitive complaint preferably corroborated by an informant B. Objective memory impairment or other cognitive for age and education C. Largely intact general cognitive function D. Essentially preserved ADL E. Not demented
Exclusion criteria are current neurological or other psychiatric disorders, as well as a history of epileptic seizures, substantial brain damage or neurosurgical operation, according to established safety criteria.