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Clinical Research Center for Dementia of South Korea (CREDOS)(or CRCD) (CREDOS)

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ClinicalTrials.gov Identifier: NCT01198093
Recruitment Status : Unknown
Verified September 2012 by Doh Kwan Kim, Samsung Medical Center.
Recruitment status was:  Recruiting
First Posted : September 9, 2010
Last Update Posted : September 28, 2012
Sponsor:
Collaborator:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The objective of this study is to present evidence-based medicine for development of clinical practice guideline through prospective study of Alzheimer's disease(AD) and mild cognitive impairment(MCI) in korea

Condition or disease
Alzheimer's Disease

Detailed Description:
The specific aims of this study is (1) construction & maintenance of cohort for Alzheimer's disease(AD) and mild cognitive impairment(MCI); (2) study of epidemiology, rate of progression, risk factor, prognostic factor; (3) study of biomarker such as neuropsychological assessment, peripheral & CSF markers, neuroimaging(both structural & functional)

Study Design

Study Type : Observational
Estimated Enrollment : 800 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical Research Center for Dementia of South Korea (CREDOS)
Study Start Date : November 2005
Estimated Primary Completion Date : August 2015
Estimated Study Completion Date : August 2015


Groups and Cohorts


Outcome Measures

Biospecimen Retention:   Samples With DNA
Serum, plasma and DNAs were prepared

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
  1. Patient populatin who is suffering from memory impairment
  2. Normal subjects matched with age and gender
Criteria

Inclusion Criteria:

  • Alzheimer's disease(AD) and mild cognitive impairment(MCI)will be enrolled in the study.

    1. the diagnostic criteria of Alzheimer's disease(AD) according to DSM IV or NINCDS -ADRDA
    2. the diagnostic criteria of mild cognitive impairment(MCI) A. Memory or other cognitive complaint preferably corroborated by an informant B. Objective memory impairment or other cognitive for age and education C. Largely intact general cognitive function D. Essentially preserved ADL E. Not demented

Exclusion Criteria:

  • Exclusion criteria are current neurological or other psychiatric disorders, as well as a history of epileptic seizures, substantial brain damage or neurosurgical operation, according to established safety criteria.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01198093


Contacts
Contact: Doh K Kim, Ph.D 82-2-3410-3582 dohkwan.kim@samsung.com

Locations
Korea, Republic of
Samsung Medical Center Recruiting
Seoul, Kangnam-Ku, Korea, Republic of, 135-710
Contact: Doh Kwan Kim, M.D and Ph.D    82-2-3410-3582    paulkim@skku.edu   
Sponsors and Collaborators
Samsung Medical Center
Ministry of Health & Welfare, Korea
Investigators
Principal Investigator: Doh K KIm, Ph.D Ministry of Health and Welfare
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Doh Kwan Kim, Professor, Samsung Medical Center
ClinicalTrials.gov Identifier: NCT01198093     History of Changes
Other Study ID Numbers: 2005-02-008
First Posted: September 9, 2010    Key Record Dates
Last Update Posted: September 28, 2012
Last Verified: September 2012

Keywords provided by Doh Kwan Kim, Samsung Medical Center:
Alzheimer's disease
Mild Cognitive Impairment
cohort study

Additional relevant MeSH terms:
Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders