Association Between Fractional Exhaled Nitric Oxide and Asthma Control (FeNO_AS)
The purpose of this study is to determine mean or median of fractional exhaled nitric oxide (FeNO) in Thai atopic asthmatic patients that divided into subgroups due to level of asthma control according to the global initiative for asthma guideline.
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||Association Between Fractional Exhaled Nitric Oxide and Asthma Control|
- fractional exhaled nitric oxide level [ Time Frame: 10 minutes (average time), on the day of enrollment ] [ Designated as safety issue: No ]
- scores of asthma control test: ACT [ Time Frame: 5 minutes (average time), on the day of enrollment ] [ Designated as safety issue: No ]
|Study Start Date:||February 2010|
|Study Completion Date:||December 2010|
|Primary Completion Date:||December 2010 (Final data collection date for primary outcome measure)|
From many previous studies, fractional exhaled nitric oxide (FeNO) has many benefits such as non-invasive, easily to perform, less time consume, has direct association with severity of inflammation of bronchial trees and sputum eosinophils, has benefit for diagnosis and monitoring the treatment in asthmatic patients.
In Thailand, this field of study is less extend, especially in children population. We hypothesized that in uncontrolled or partly controlled group may have high level of fractional exhaled nitric oxide (FeNO) than controlled group.
It is therefore desirable to examine the association between fractional exhaled nitric oxide (FeNO) and level of asthma control among atopic asthmatic Thai children and will be the main objective of this research.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01197690
|Principal Investigator:||Professor Nualanong Visitsunthorn, MD||Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University|