Blood Pressure Level and Prognosis in Acute Stroke
|ClinicalTrials.gov Identifier: NCT01195350|
Recruitment Status : Unknown
Verified July 2011 by UPECLIN HC FM Botucatu Unesp.
Recruitment status was: Recruiting
First Posted : September 6, 2010
Last Update Posted : July 6, 2011
Stroke is the leading cause of mortality in Brazil. Strict blood pressure control in chronic phase is the major measure to primary and secondary prevention, but in acute phase is not clear the best blood pressure level. Few studies demonstrate a "U" relationship between blood pressure and lethality; nevertheless any Brazilian study has addressed this issue.
This is a prospective observational study on the relationship between BP and mortality in the acute phase of stroke. The study will be conducted in the Adult ICU of HC-UNESP. Will be analyzed 266 patients aged 18 years and of both sexes admitted to the ICU with a diagnosis of hemorrhagic and ischemic stroke. Participants will be divided into three groups according to the initial PA present:
Group A: Patients with systolic BP of entry below 140 mmHg; Group B: Patients with systolic BP of entry between 140 and 180 mmHg; Group C: patients with systolic BP greater than 180 mmHg entry. Multiple logistic regression analysis will be done to verify the association of blood pressure and lethality adjusted to confounding variables.
|Condition or disease|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||266 participants|
|Official Title:||Relationship Between Blood Pressure Level and Lethality in Acute Phase of Stroke : Observational Prospective Study.|
|Study Start Date :||February 2010|
|Estimated Primary Completion Date :||December 2011|
|Estimated Study Completion Date :||December 2011|
- Death [ Time Frame: 1 week ]
- Physical incapacity [ Time Frame: one month ]Modified Rankin scale will be applied within one month after the cerebrovascular event.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01195350
|Unidades de Terapia Intensiva do Hospital das Clínicas da Faculdade de Medicina de Botucatu||Recruiting|
|Botucatu, São Paulo, Brazil|
|Contact: Natalia Furlan firstname.lastname@example.org|
|Principal Investigator:||Natalia E Furlan, Bacharel||Faculdade de Medicina de Botucatu|
|Study Chair:||Rodrigo Bassan, MSc||Faculdade de Medicina de Botucatu|
|Study Director:||Luis C Martin, Phd||Faculdade de Medicina de Botucatu|