Assessment of Dietary Protein Needs of Older Women
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01193946|
Recruitment Status : Completed
First Posted : September 2, 2010
Last Update Posted : January 17, 2013
The purpose of this study is to evaluate dietary protein requirements in elderly women aged 80 years and older using the indicator amino acid oxidation technique.
Hypothesis to be tested: Protein requirement for elderly women is higher than the estimated average requirement of 0.66 g∙kg-1∙d-1 protein. The recommended protein intake for elderly women is higher than the recommended dietary allowance of 0.80 g∙kg-1∙d-1 protein.
|Condition or disease||Intervention/treatment|
|Protein-energy; Imbalance||Dietary Supplement: dietary control|
|Study Type :||Observational|
|Actual Enrollment :||8 participants|
|Official Title:||Assessment of Dietary Protein Needs of Older Women|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||November 2011|
|Actual Study Completion Date :||December 2011|
There is currently considerable debate regarding the accuracy of the estimated average requirement (EAR) and the recommended dietary allowance (RDA) for older people. Very limited data obtained from older individuals are available to support the assumption that age does not affect protein requirement. Existing method like nitrogen balance has inherent limitations that diminish it from being considered a reference method. Indicator amino acid oxidation technique is emerging as an alternative method to measure dietary protein requirement. It is more accurate and less demanding. The current study will be the first time this technique is used with elderly adults and will provide an important foundation for geriatric nutrition research
Dietary Supplement: dietary control
Seven dietary protein levels will be tested randomly on the 7 testing days: 0.10, 0.30, 0.60, 0.90, 1.2, 1.5, and 1.8 g∙kg-1∙d-1.
- dietary protein requirement in older women [ Time Frame: 3 month ]Dietary protein requirement is assessed by the subjects' differential response to different dietary protein intake
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01193946
|United States, Indiana|
|W Lafayette, Indiana, United States, 47907|
|Principal Investigator:||Wayne W Campbell, Ph.D.||Purdue University|