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Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes (EXPLORE)

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ClinicalTrials.gov Identifier: NCT01192425
Recruitment Status : Completed
First Posted : September 1, 2010
Last Update Posted : September 1, 2010
Sponsor:
Information provided by:
Alexion Pharmaceuticals

Brief Summary:
Examine red and white blood cells of PNH patients with bone marrow failure syndromes.

Condition or disease
Hemoglobinuria

Study Type : Observational
Actual Enrollment : 5580 participants
Time Perspective: Prospective
Official Title: P06-001: (EX)Amination of (P)NH, by (L)Evel (O)f CD59 on (RE)d and White Blood Cells, in Bone Marrow Failure Syndromes






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Ages Eligible for Study:   10 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients at least 10 years of age with aplastic anemia, myelodyplastic syndromes or other bone marrow failure syndromes.
Criteria

Inclusion Criteria:

  • At least 10 years of age.
  • Has aplastic anemia, myelodysplastic syndromes or other bone marrow failure syndromes

Exclusion Criteria:

  • Has any condition that might interfere with the patient's participation

Responsible Party: Michael Bombara, Senior Director, Global Clinical Operations, Alexion Pharmaceuticals, Inc.
ClinicalTrials.gov Identifier: NCT01192425     History of Changes
Other Study ID Numbers: P06-001
First Posted: September 1, 2010    Key Record Dates
Last Update Posted: September 1, 2010
Last Verified: August 2010

Keywords provided by Alexion Pharmaceuticals:
PNH clone cells
Aplastic Anemia
AA
Myelodysplastic Syndromes
MDS
bone marrow failure syndromes
FLAER
Paroxysmal Nocturnal Hemoglobinuria

Additional relevant MeSH terms:
Syndrome
Hemoglobinuria
Hemoglobinuria, Paroxysmal
Pancytopenia
Anemia, Aplastic
Disease
Pathologic Processes
Proteinuria
Urination Disorders
Urologic Diseases
Urological Manifestations
Signs and Symptoms
Anemia, Hemolytic
Anemia
Hematologic Diseases
Myelodysplastic Syndromes
Bone Marrow Diseases