Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes (EXPLORE)

This study has been completed.
Information provided by:
Alexion Pharmaceuticals Identifier:
First received: August 30, 2010
Last updated: August 31, 2010
Last verified: August 2010
Examine red and white blood cells of PNH patients with bone marrow failure syndromes.


Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: P06-001: (EX)Amination of (P)NH, by (L)Evel (O)f CD59 on (RE)d and White Blood Cells, in Bone Marrow Failure Syndromes

Resource links provided by NLM:

Further study details as provided by Alexion Pharmaceuticals:

Enrollment: 5580

Ages Eligible for Study:   10 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients at least 10 years of age with aplastic anemia, myelodyplastic syndromes or other bone marrow failure syndromes.

Inclusion Criteria:

  • At least 10 years of age.
  • Has aplastic anemia, myelodysplastic syndromes or other bone marrow failure syndromes

Exclusion Criteria:

  • Has any condition that might interfere with the patient's participation
  Contacts and Locations
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No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Michael Bombara, Senior Director, Global Clinical Operations, Alexion Pharmaceuticals, Inc. Identifier: NCT01192425     History of Changes
Other Study ID Numbers: P06-001
Study First Received: August 30, 2010
Last Updated: August 31, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by Alexion Pharmaceuticals:
PNH clone cells
Aplastic Anemia
Myelodysplastic Syndromes
bone marrow failure syndromes
Paroxysmal Nocturnal Hemoglobinuria

Additional relevant MeSH terms:
Hemoglobinuria, Paroxysmal
Anemia, Hemolytic
Bone Marrow Diseases
Hematologic Diseases
Myelodysplastic Syndromes
Signs and Symptoms
Urination Disorders
Urologic Diseases
Urological Manifestations processed this record on November 25, 2015