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Radiation Planning Study for High Grade Brain Tumors

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01191346
First Posted: August 30, 2010
Last Update Posted: August 22, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Alison Kastl, BS, CCRC, University of Cincinnati
  Purpose
The purpose of this research study is to see if a higher strength MRI procedure provides better images to use in planning radiation treatments for patients with brain tumors in the future.

Condition Intervention
High Grade Glioma Other: 3T MRI

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: 3T Versus 1.5T MR Approaches in Target Definition for Malignant Gliomas: Is There a Significant Difference in Tumor Extent and Radiation Treatment Volume?

Resource links provided by NLM:


Further study details as provided by Alison Kastl, BS, CCRC, University of Cincinnati:

Primary Outcome Measures:
  • Treatment volume [ Time Frame: 1 year average ]
    To assess the difference in treatment volume for radiation planning in gliomas as calculated using 1.5T versus 3T magnets


Enrollment: 24
Study Start Date: June 2010
Study Completion Date: March 2013
Primary Completion Date: March 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
3T MRI
Patients receiving 3T MRI
Other: 3T MRI
3T MRI in addition to standard 1.5T MRI for treatment planning

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with high grade glioma planning to receive radiation therapy
Criteria

Inclusion Criteria:

  • Histologically confirmed, newly diagnosed Grade III-IV glioma
  • Planning to undergo radiation therapy

Exclusion Criteria:

  • Grade I or II glioma
  • Patients unable to undergo MRI imaging
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01191346


Locations
United States, Ohio
University of Cincinnati
Cincinnati, Ohio, United States, 45219
Sponsors and Collaborators
University of Cincinnati
Investigators
Principal Investigator: Jessica Guarnaschelli, MD University of Cincinnati
  More Information

Responsible Party: Alison Kastl, BS, CCRC, Director of Clinical Trials, University of Cincinnati
ClinicalTrials.gov Identifier: NCT01191346     History of Changes
Other Study ID Numbers: BTC-G1
First Submitted: August 25, 2010
First Posted: August 30, 2010
Last Update Posted: August 22, 2017
Last Verified: December 2014
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Additional relevant MeSH terms:
Glioma
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue