Treatment for Young Adults With Anorexia Nervosa
|Anorexia Nervosa||Behavioral: Out-Patient Psychotherapy Treatment||Phase 1 Phase 2|
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Family-Based Treatment for Weight Restoration in Young Adults With Anorexia Nervosa|
- Weight (BMI) [ Time Frame: 6 months of treatment ]
- Changes in shape and weight concerns as measured with Eating Disorder Examination subscales [ Time Frame: 18 therapy sessions or 6 months of treatment ]
|Study Start Date:||July 2010|
|Study Completion Date:||April 2016|
|Primary Completion Date:||April 2016 (Final data collection date for primary outcome measure)|
|Experimental: Family Based Treatment||
Behavioral: Out-Patient Psychotherapy Treatment
Individual and Group Therapy Sessions
Anorexia Nervosa (AN) is a serious psychiatric illness that occurs in an estimated 0.5 to 3.7% of women. The illness severely affects physical, emotional, and social functioning. The mortality rates associated with this severely disabling condition are higher than those for any other psychiatric disorder and substantially higher than those expected in the general population. Lower weight at presentation, longer illness duration, and alcohol abuse are associated with a higher risk of mortality.
Treatment-outcome for adult AN is poor with a quarter of adults with AN having poor outcome. In AN, promising outcomes are seen in family-based treatment (FBT) for adolescent patients who present between the ages of 12 to 18 with a short duration of illness. A manualized version of FBT has now been tested in several studies and case series, showing that well over 80% of participants had good or intermediate outcome at post-treatment. Despite its efficacy with adolescents, FBT has not been utilized with young adults.
The purpose of this study is to develop and refine FBT to promote weight gain in young adults with Anorexia Nervosa.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01190423
|United States, Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19122|
|Principal Investigator:||Eunice Y Chen, PhD||Temple University|