Grape Seed Extract and Postprandial Oxidation and Inflammation (GSEMetS)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01190358|
Recruitment Status : Completed
First Posted : August 27, 2010
Last Update Posted : July 19, 2017
|Condition or disease||Intervention/treatment||Phase|
|Metabolic Syndrome||Dietary Supplement: Placebo Dietary Supplement: Grape seed extract||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||12 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Grape Seed Extract and Postprandial Oxidation and Inflammation: A Pilot Study in People With the Metabolic Syndrome.|
|Actual Study Start Date :||August 2010|
|Actual Primary Completion Date :||March 2011|
|Actual Study Completion Date :||September 2015|
Placebo Comparator: Placebo
Dietary Supplement: Placebo
Sugar pill containing maltodextrin.
Other Name: Placebo, non-active components
Active Comparator: Grape seed extract
300mg of grape seed extract.
Dietary Supplement: Grape seed extract
Meganatural Gold® contains 300mg of grape seed extract.
Other Name: Active, Meganatural Gold®
- Modification of the postprandial inflammatory response. [ Time Frame: 7 hours ]
Analysis of inflammatory markers known to increase following a meal high in fat (~40% kcal from fat). Markers to be analyzed will include the following:
- Serum lipids
- Oxidized LDL
- Metabolic response to a high fat meal. [ Time Frame: 7 hours ]Assay for the insulin and glucose response generated from consumming a high fat meal (~40% of kcal from fat).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01190358
|United States, California|
|University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility)|
|Davis, California, United States, 95616|
|VA Hospital, Mather|
|Mather, California, United States, 95655|
|Principal Investigator:||Chulani T Kappagoda, M.D., Ph. D.||University of California, Davis|