Integrating Interventions for Maternal Substance Abuse (ITSAN)

This study has been completed.
Information provided by (Responsible Party):
Lisa Saldana, Oregon Social Learning Center Identifier:
First received: August 23, 2010
Last updated: April 27, 2015
Last verified: April 2015
This Research Plan proposes Stage 1 Research integrating evidence based practices to address the needs of mothers referred to child welfare for substance abuse. Mothers with a history of methamphetamine abuse and child neglect will be recruited. Using an intensive community based treatment, mothers will receive substance abuse treatment combined with parenting skills training and psychosocial support for basic needs (e.g., housing, employment). This project will include a feasibility study (n = 5), followed by a small randomized pilot (n = 24) to examine the efficacy of the Integrated Treatment for Substance Abuse and Neglect compared to treatment as usual, with a population of substance abusing neglectful mothers referred through the Department of Child Welfare.

Condition Intervention Phase
Substance Abuse
Child Neglect
Behavioral: ITSAN
Behavioral: Services as Usual
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Integrating Interventions for Maternal Substance Abuse and Child Neglect

Resource links provided by NLM:

Further study details as provided by Oregon Social Learning Center:

Primary Outcome Measures:
  • Addiction Severity Index [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
    self report of all substances used

  • Service Utilization Survey [ Time Frame: monthly ] [ Designated as safety issue: No ]
    self report of social, medical, and mental health services received by parent and youth

  • Parenting Measures [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
    Assessment battery of parenting beliefs, expectations, and behaviors

Secondary Outcome Measures:
  • Urinalysis [ Time Frame: monthly ] [ Designated as safety issue: No ]
    10 panel Urine Drug Screen Collection

  • Archival data from the Child Welfare system [ Time Frame: annually ] [ Designated as safety issue: No ]
    System level data of new reports to the child welfare system

Enrollment: 31
Study Start Date: September 2007
Study Completion Date: August 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Integrated Behavioral Treatment
Combined substance abuse, parenting skills, and basic needs intervention
Behavioral: ITSAN
integrated behavioral intervention for substance abuse, parenting skills, and basic needs
Active Comparator: casework treatment as usual
services as usual as referred by child welfare
Behavioral: Services as Usual
Services as usual referred by child welfare


Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Maternal Substance Abuse
  • Child Welfare involvement
  • Child Neglect
  • English Speaking
  • Child either remaining in the home or reunification plan in place
  • Living in the county

Exclusion Criteria:

  • Current involvement in other substance abuse treatment
  • Current involvement in other parenting skills training
  • parental rights terminated
  • active psychosis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01188434

United States, Oregon
Eugene, Oregon, United States, 97401
Sponsors and Collaborators
Oregon Social Learning Center
Principal Investigator: Lisa Saldana, PhD OSLC Community Programs
  More Information

No publications provided

Responsible Party: Lisa Saldana, Research Scientist, Oregon Social Learning Center Identifier: NCT01188434     History of Changes
Other Study ID Numbers: K23DA21603
Study First Received: August 23, 2010
Last Updated: April 27, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by Oregon Social Learning Center:
Substance Abuse
Child Neglect
Child Welfare
Evidence Based Practice

Additional relevant MeSH terms:
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders processed this record on November 27, 2015