Computed Tomography (CT) Colonography Versus Optical Colonoscopy
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ClinicalTrials.gov Identifier: NCT01181739
Recruitment Status : Unknown
Verified April 2013 by University of British Columbia. Recruitment status was: Recruiting
This study is designed to compare traditional Colonoscopy with CT Colonography, commonly known as "virtual colonoscopy". The study will compare the ability of both procedures as screening tests to identify polyps in the colon in patients at average risk for developing polyps. The patient preferences for each procedure will be assessed by means of a standardized questionnaire. As well the ability observers with differing levels of experience to read the CT scans and detect polyps will be compared. All patients will receive both CT scans and traditional colonoscopy on the same day.
CT colonography (CTC), is a promising alternative to optical colonoscopy for use in widespread screening, as it requires no intravenous administration of sedatives or analgesia and little recovery time.
Biospecimen Retention: Samples Without DNA
Colonic Mucosal Biopsy specimens obtained at the time of colonoscopy
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Ages Eligible for Study:
19 Years to 65 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients 19 - 65 years of age at with a recognized indication for optical colonoscopy, including those high risk for colorectal cancer.
19 - 65 years of age
Have a recognized indication for optical colonoscopy, including high risk for colorectal cancer
Over 45 years of age with a family history of colorectal cancer, those with positive screening tests (FOBT, DRE, flexible sigmoidoscopy and contrast enema)
Previous history of advanced adenomas and those with suggestive symptoms and signs (bleeding, abdominal pain, anemia)
Must be able to read and understand English and must be able to give informed consent