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The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases

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ClinicalTrials.gov Identifier: NCT01180868
Recruitment Status : Completed
First Posted : August 12, 2010
Last Update Posted : July 31, 2012
Sponsor:
Information provided by (Responsible Party):
Jonsson Comprehensive Cancer Center

Study Description
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
The purpose of this study is to determine the biodistribution of a new agent 1-L-(2 deoxy-2,-18fluoroarabinofuranosyl) cytosine non-invasively in healthy humans and to evaluate whether it can be used to image cancer, autoimmune disease, and inflammation

Condition or disease
Autoimmune Diseases Cancer

Study Design
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Study Type : Observational
Actual Enrollment : 1 participants
Official Title: The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases
Study Start Date : May 2008
Actual Primary Completion Date : November 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Group/Cohort
patients with cancer
patients with hematological malignancies and solid tumors
patients with autoimmune dosorders
patients with Rheumatoid arthritis, Crohns's disease, systemic lupus erythematosus.
healthy subjects


Outcome Measures
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Eligibility Criteria
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with cancer, patients with autoimmune dosorders, and healthy subjects.
Criteria

Inclusion Criteria:

  • greater than 18 years of age
  • women of childbearing potential will undergo a pregnancy test free of charge
  • patients with hematological malignancies, solid tumors or autoimmune disorders
Contacts and Locations
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01180868


Locations
United States, California
UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
Jonsson Comprehensive Cancer Center
Investigators
Principal Investigator: Christiaan Schiepers, M.D. Ph.D University of California, Los Angeles
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Responsible Party: Jonsson Comprehensive Cancer Center
ClinicalTrials.gov Identifier: NCT01180868     History of Changes
Other Study ID Numbers: 08-02-049
DE-PS02-08ER08-01 ( Other Grant/Funding Number: Department of Energy )
CIRM No. RT1-01126-1 ( Other Grant/Funding Number: California Institute for Regenerative Medicine )
First Posted: August 12, 2010    Key Record Dates
Last Update Posted: July 31, 2012
Last Verified: July 2012

Keywords provided by Jonsson Comprehensive Cancer Center:
imaging probe
cancer
inflammatory tissue
inflammatory diseases

Additional relevant MeSH terms:
Autoimmune Diseases
Immune System Diseases