Study of Treatment Choice in Patients With Localized Prostate Cancer
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|ClinicalTrials.gov Identifier: NCT01177865|
Recruitment Status : Unknown
Verified November 2010 by National Cancer Institute (NCI).
Recruitment status was: Recruiting
First Posted : August 9, 2010
Last Update Posted : August 26, 2013
RATIONALE: Gathering information about patients with prostate cancer may help doctors learn more about how patients choose treatment options.
PURPOSE: This study is looking at treatment choice in patients with localized prostate cancer.
|Condition or disease||Intervention/treatment||Phase|
|Prostate Cancer||Other: informational intervention Other: questionnaire administration||Not Applicable|
- To evaluate the importance of prostate cancer treatment characteristics to men with localized prostate cancer.
- To determine to what extent men will choose the strengths and weaknesses of one treatment over a different set of strengths and weaknesses of another treatment when making a choice between them.
- To determine the correlation between attributes that are important to men and baseline demographics, functional status, and disease risk characteristics.
OUTLINE: This is a multicenter study.
Patients complete a 'discrete choice experiment' questionnaire presenting three treatment options based on 8 aspects of treatment. Attributes relevant to men with prostate cancer (e.g., sexual health, urinary function, return to normal activities [work, gardening, sports, shopping]) that apply to surveillance, radical therapies and new minimally-invasive therapies have been selected for consideration. Baseline demographics such as age, working/retired/unemployed/household income, prostate cancer characteristics (PSA level, Gleason grade, stage), baseline functional status (genitourinary function), and final treatment choice will also be collected in order to ascertain whether there is any relationship and association between patient preferences for treatment and these baseline demographics. Individuals will be asked to choose between the three treatment profiles.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||432 participants|
|Primary Purpose:||Health Services Research|
|Official Title:||Evaluating Patient Preferences for the Treatment of Localized Prostate Cancer - A Discrete Choice Experiment|
|Study Start Date :||September 2010|
|Estimated Primary Completion Date :||September 2012|
- Preferences for, and trade-offs between, the attributes of pre-treatment evaluation with general anaesthetic biopsies and post-treatment frequency of biopsies
- Treatment choice in respect to risks to sexual function and urinary function, return to normal activities, aim to treat the whole gland or only cancer areas or important cancer areas, retreatment rate, and mortality rate
- Correlation between attributes important to men and baseline demographics, functional status, and disease risk characteristics
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01177865
|University College of London Hospitals||Recruiting|
|London, England, United Kingdom, WIT 3AA|
|Contact: Contact Person 44-20-7380-9194 email@example.com|
|Principal Investigator:||Mark Emberton, MD, FRCS, MBBS||University College London Hospitals|