Proteomic Analysis of Human Hepatocellular Carcinoma

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2009 by Far Eastern Memorial Hospital.
Recruitment status was  Recruiting
Information provided by:
Far Eastern Memorial Hospital Identifier:
First received: June 2, 2009
Last updated: August 5, 2010
Last verified: June 2009
This is a pilot study to evaluate the difference between the protein expression between hepatocellular carcinoma and tumor with vessel invasion in Asian patients with hepatocellular carcinoma.

Condition Intervention
Carcinoma, Hepatocellular
Procedure: Operation

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Proteomic Analysis of Human Hepatocellular Carcinoma Associated With Portal Vein Thrombosis

Resource links provided by NLM:

Further study details as provided by Far Eastern Memorial Hospital:

Primary Outcome Measures:
  • Recurrence [ Time Frame: one year ] [ Designated as safety issue: No ]
    Evidence of clinically definite vascular invasion of hepatocellular carcinoma. Confirmed by operation. Compare the proteomic expression of tumor, non-tumor ans tumor tissue in vascular part.

Estimated Enrollment: 150
Study Start Date: February 2009
Estimated Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Operation
    Operation for clinically evaluated resectable hepatocelluar carcinoma. Compare the different expression of protein between tumor, non-tumor and tumor with vascular invasion part.

Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Arm A: Hepatocellular carcinoma with vessel invasion:

  • hepatocellular carcionoma, pathologic diagnosed.
  • image documented vessel invasion, including portal vein thrombosis
  • eligible for surgical intervension.

Arm B: hepatocellular carcinoma without vessel invasion:

  • hepatocellular carcinoma, pathologic diagnosed or clinical diagnosed according to EASL criteria.
  • no vessel invasion on image.

Arm C: Healthy hepatitis carrier:

  • patients age >18 years old with hepatitis B or C
  • normal liver function.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01177631

Far Eastern Memorial Hospital Recruiting
Taipei, Taiwan, 220
Contact: Meng-Tzu Weng, MD    866-2-89667000 ext 1745   
Sponsors and Collaborators
Far Eastern Memorial Hospital
  More Information

No publications provided

Responsible Party: Meng-Tzu Weng Identifier: NCT01177631     History of Changes
Other Study ID Numbers: 97068
Study First Received: June 2, 2009
Last Updated: August 5, 2010
Health Authority: Taiwan: Institutional Review Board

Keywords provided by Far Eastern Memorial Hospital:
Carcinoma, hepatocellular
Portal vein

Additional relevant MeSH terms:
Carcinoma, Hepatocellular
Digestive System Diseases
Digestive System Neoplasms
Liver Diseases
Liver Neoplasms
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Glandular and Epithelial processed this record on November 27, 2015