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Laser Resurfacing Versus Dermabrasion for Scar Revision

This study has been completed.
Information provided by (Responsible Party):
University of Minnesota - Clinical and Translational Science Institute Identifier:
First received: June 21, 2010
Last updated: June 25, 2013
Last verified: June 2013
Dermabrasion has been the historical standard used for resurfacing scars on the skin. Recently, fractionated laser therapy has been FDA approved for scar resurfacing. This study intends to compare dermabrasion versus fractionated laser therapy for scar resurfacing.

Condition Intervention
Coagulation, Laser
Device: Fractionated laser
Device: Dermabrasion

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: A Comparison Evaluation of Fractional Laser Therapy and Dermabrasion for Scar Revision

Resource links provided by NLM:

Further study details as provided by University of Minnesota - Clinical and Translational Science Institute:

Primary Outcome Measures:
  • Safey Data Score Based on Ordinal Ratings of Erythema, Edema, Bleeding, Eschar After Resurfacing [ Time Frame: Day 0, Week1, Month 1 ]
    Erythema, edema, bleeding, and eschar after resurfacing were used as indicators of safety. Each was judged based on a 4 point ordinal scale 0=absent, 1=mild, 2=moderate, 3=severe.

Secondary Outcome Measures:
  • Visual Analog Scale for Assessing Scar Improvement. [ Time Frame: 3 months ]

    Visual Analog Scale for assessing scar improvement. 0 : Worsening or no improvement

    1. : 1-25% improvement
    2. : 26-50% improvement
    3. : 51-75% improvement
    4. : 76-100% improvement

Enrollment: 6
Study Start Date: April 2010
Study Completion Date: September 2010
Primary Completion Date: August 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Fractionated laser
This Arm is the section of scar that will be treated with Fractionated Laser
Device: Fractionated laser
Fractionated laser in the form of the Re:Pair CO2 laser manufactured by Solta Medical.
Active Comparator: Dermabrasion
Dermabrasion is the gold standard for scar resurfacing and will be used as the control against which Fractionated Laser is compared.
Device: Dermabrasion
Diamond Fraise Dermabrasion will be performed in standard fashion down to papillary dermis.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Post-surgical or post traumatic scar on face or scalp.
  • Age 18 or older
  • Able to read and comprehend English
  • Willing to follow treatment schedule and post treatment care requirements
  • Signed the informed consent form
  • Fitzpatrick skin type I-III

Exclusion Criteria:

  • known photosensitivity
  • Taken any medications known to induce photosensitivity in previous three months
  • Taken Accutane within past 12 months
  • Pregnant or nursing
  • Currently on topical or oral antibiotics
  • Immunocompromised status
  • Skin type IV or greater
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01176448

United States, Minnesota
Zel Skin and Laser
Edina, Minnesota, United States, 55424
Sponsors and Collaborators
University of Minnesota - Clinical and Translational Science Institute
Principal Investigator: John J Christophel, MD University of Minnesota - Clinical and Translational Science Institute
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: University of Minnesota - Clinical and Translational Science Institute Identifier: NCT01176448     History of Changes
Other Study ID Numbers: UMN-1001M75732
Study First Received: June 21, 2010
Results First Received: November 9, 2011
Last Updated: June 25, 2013

Keywords provided by University of Minnesota - Clinical and Translational Science Institute:
Coagulation, Laser

Additional relevant MeSH terms:
Pathologic Processes processed this record on April 26, 2017