The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia
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|ClinicalTrials.gov Identifier: NCT01175746|
Recruitment Status : Completed
First Posted : August 5, 2010
Last Update Posted : June 13, 2013
|Condition or disease||Intervention/treatment||Phase|
|Healthy Subjects||Drug: Nicardipine Drug: remifentanil||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||46 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Study Start Date :||August 2010|
|Actual Primary Completion Date :||June 2011|
|Actual Study Completion Date :||December 2011|
|Active Comparator: remifentanil||
0.1-0.5 ugkg/min during hypotensive anesthesia
Other Name: ultiva®
- Creatinine Clearance [ Time Frame: 2hr after the start of hypotensive anesthesia ]
Hypotensive anesthesia means that we maintain the mean blood pressure between 55 & 65 mmHg during surgery to decrease the blood loss.
The specific time point is exactly 2hr after we star to lower the blood pressure.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01175746
|Principal Investigator:||Ji Young Kim||Severance hospital, YUHS|