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Cognitive Remediation and Functional Skills Training in Schizophrenia

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ClinicalTrials.gov Identifier: NCT01175642
Recruitment Status : Completed
First Posted : August 5, 2010
Last Update Posted : November 17, 2016
Sponsor:
Information provided by (Responsible Party):
Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression

Brief Summary:
This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.

Condition or disease Intervention/treatment Phase
Schizophrenia Schizoaffective Disorder Behavioral: Cognitive Remediation Behavioral: FAST Early Phase 1

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 75 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia
Study Start Date : July 2007
Primary Completion Date : August 2010
Study Completion Date : September 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Schizophrenia
U.S. FDA Resources

Arm Intervention/treatment
Experimental: Cognitive remediation
Cognitive remediation
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Active Comparator: Functional Adaptive Skills Training
Functional and social skills group treatment
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills
Active Comparator: Combined Treatment
Combined cognitive remediation and functional adaptive skills training
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills



Primary Outcome Measures :
  1. neurocognition [ Time Frame: 12 weeks ]

Secondary Outcome Measures :
  1. functional competence [ Time Frame: 12 weeks ]
    performance-based measures of functional and social competence

  2. neurocognition [ Time Frame: 24 weeks ]
  3. neurocognition [ Time Frame: 36 weeks ]
  4. functional competence [ Time Frame: 24 weeks ]
  5. functional competence [ Time Frame: 36 weeks ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Enrolled in outpatient mental health care
  • Reading level of 6th grade or higher
  • English speaking

Exclusion Criteria:

  • Medical conditions known to affect cognition

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01175642


Locations
Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6
Sponsors and Collaborators
National Alliance for Research on Schizophrenia and Depression
Investigators
Principal Investigator: Christopher R Bowie, PhD Queen's University

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Christopher R. Bowie, Professor, National Alliance for Research on Schizophrenia and Depression
ClinicalTrials.gov Identifier: NCT01175642     History of Changes
Other Study ID Numbers: PSYC-085-08
First Posted: August 5, 2010    Key Record Dates
Last Update Posted: November 17, 2016
Last Verified: August 2010
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression:
Schizophrenia
Psychosis
Schizoaffective Disorder

Additional relevant MeSH terms:
Schizophrenia
Psychotic Disorders
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders