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Cognitive Remediation and Functional Skills Training in Schizophrenia

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01175642
First Posted: August 5, 2010
Last Update Posted: November 17, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression
  Purpose
This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.

Condition Intervention Phase
Schizophrenia Schizoaffective Disorder Behavioral: Cognitive Remediation Behavioral: FAST Early Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia

Resource links provided by NLM:


Further study details as provided by Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression:

Primary Outcome Measures:
  • neurocognition [ Time Frame: 12 weeks ]

Secondary Outcome Measures:
  • functional competence [ Time Frame: 12 weeks ]
    performance-based measures of functional and social competence

  • neurocognition [ Time Frame: 24 weeks ]
  • neurocognition [ Time Frame: 36 weeks ]
  • functional competence [ Time Frame: 24 weeks ]
  • functional competence [ Time Frame: 36 weeks ]

Enrollment: 75
Study Start Date: July 2007
Study Completion Date: September 2010
Primary Completion Date: August 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Cognitive remediation
Cognitive remediation
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Active Comparator: Functional Adaptive Skills Training
Functional and social skills group treatment
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills
Active Comparator: Combined Treatment
Combined cognitive remediation and functional adaptive skills training
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Enrolled in outpatient mental health care
  • Reading level of 6th grade or higher
  • English speaking

Exclusion Criteria:

  • Medical conditions known to affect cognition
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01175642


Locations
Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6
Sponsors and Collaborators
National Alliance for Research on Schizophrenia and Depression
Investigators
Principal Investigator: Christopher R Bowie, PhD Queen's University
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Christopher R. Bowie, Professor, National Alliance for Research on Schizophrenia and Depression
ClinicalTrials.gov Identifier: NCT01175642     History of Changes
Other Study ID Numbers: PSYC-085-08
First Submitted: August 3, 2010
First Posted: August 5, 2010
Last Update Posted: November 17, 2016
Last Verified: August 2010
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression:
Schizophrenia
Psychosis
Schizoaffective Disorder

Additional relevant MeSH terms:
Schizophrenia
Psychotic Disorders
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders