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Implication of CD35, CD21 and CD55 in Exudative Age-related Macular Degeneration

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2010 by Rudolf Foundation Clinic.
Recruitment status was:  Active, not recruiting
Information provided by:
Rudolf Foundation Clinic Identifier:
First received: November 19, 2008
Last updated: August 2, 2010
Last verified: August 2010
The purpose of this study is to determine a possible implication of CD21, CD35 and CD55 in the pathogenesis of age-related macular degeneration. The aim is to asses a difference in expression rates of these factors on AMD-patients and a healthy control group.

Condition Intervention
Age-Related Macular Degeneration
Other: cd 35, cd21, cd55

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Is CD35, CD21 and CD55 Associated With Exudative Age-related Macular Degeneration

Resource links provided by NLM:

Further study details as provided by Rudolf Foundation Clinic:

Primary Outcome Measures:
  • determine a possible implication of CD21, CD35 and CD55 in the pathogenesis of age-related macular degeneration [ Time Frame: 1 day ]

Secondary Outcome Measures:
  • expression rates of on AMD-patients and a healthy control group [ Time Frame: 1 year ]

Estimated Enrollment: 120
Study Start Date: September 2008
Estimated Study Completion Date: August 2010
Estimated Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
cd35 Other: cd 35, cd21, cd55
Blood drawing/ 10ml/ once- duration of 1 day of full examination of the patient


Ages Eligible for Study:   55 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients with exudative age-related macular degeneration, over 55

Inclusion Criteria:

  • Man and women over 18 years old
  • Filled out informed consent
  • Diagnosis of non-exudative/ exudative age related macular degeneneration

Exclusion Criteria:

  • Inherited retinal diseases
  • Other acquired retinal/ macular
  • Missing informed consent
  Contacts and Locations
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Please refer to this study by its identifier: NCT01174407

Rudolf Foundation Clinic
Vienna, Austria, 1030
Sponsors and Collaborators
Rudolf Foundation Clinic
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Prof. Dr. Susanne Binder, Rudolf Foundation Clinic Identifier: NCT01174407     History of Changes
Other Study ID Numbers: EK08010-VK
Study First Received: November 19, 2008
Last Updated: August 2, 2010

Additional relevant MeSH terms:
Macular Degeneration
Wet Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases processed this record on May 25, 2017