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Implication of CD35, CD21 and CD55 in Exudative Age-related Macular Degeneration

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ClinicalTrials.gov Identifier: NCT01174407
Recruitment Status : Unknown
Verified August 2010 by Rudolf Foundation Clinic.
Recruitment status was:  Active, not recruiting
First Posted : August 3, 2010
Last Update Posted : August 3, 2010
Sponsor:
Information provided by:
Rudolf Foundation Clinic

Brief Summary:
The purpose of this study is to determine a possible implication of CD21, CD35 and CD55 in the pathogenesis of age-related macular degeneration. The aim is to asses a difference in expression rates of these factors on AMD-patients and a healthy control group.

Condition or disease Intervention/treatment
Age-Related Macular Degeneration Other: cd 35, cd21, cd55

Study Type : Observational
Estimated Enrollment : 120 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Is CD35, CD21 and CD55 Associated With Exudative Age-related Macular Degeneration
Study Start Date : September 2008
Estimated Primary Completion Date : December 2009
Estimated Study Completion Date : August 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort Intervention/treatment
cd35 Other: cd 35, cd21, cd55
Blood drawing/ 10ml/ once- duration of 1 day of full examination of the patient



Primary Outcome Measures :
  1. determine a possible implication of CD21, CD35 and CD55 in the pathogenesis of age-related macular degeneration [ Time Frame: 1 day ]

Secondary Outcome Measures :
  1. expression rates of on AMD-patients and a healthy control group [ Time Frame: 1 year ]


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Ages Eligible for Study:   55 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients with exudative age-related macular degeneration, over 55
Criteria

Inclusion Criteria:

  • Man and women over 18 years old
  • Filled out informed consent
  • Diagnosis of non-exudative/ exudative age related macular degeneneration

Exclusion Criteria:

  • Inherited retinal diseases
  • Other acquired retinal/ macular
  • Missing informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01174407


Locations
Austria
Rudolf Foundation Clinic
Vienna, Austria, 1030
Sponsors and Collaborators
Rudolf Foundation Clinic

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Prof. Dr. Susanne Binder, Rudolf Foundation Clinic
ClinicalTrials.gov Identifier: NCT01174407     History of Changes
Other Study ID Numbers: EK08010-VK
First Posted: August 3, 2010    Key Record Dates
Last Update Posted: August 3, 2010
Last Verified: August 2010

Additional relevant MeSH terms:
Macular Degeneration
Wet Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases