Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?

This study has been completed.
Information provided by:
Mansoura University Identifier:
First received: July 30, 2010
Last updated: August 13, 2010
Last verified: October 2010
Total proctocolectomy with ileal pouch anal anastomosis is the first choice surgical operation for management of ulcerative colitis and familial adenomatous polyposis. The addition of diverting ileostomy may reduce septic complications. In this randomized study the investigators compare two groups of patients with stapled ileoanal pouch one of them had diverting ileostomy and in the other this step is omitted.

Condition Intervention
Ulcerative Colitis
Familial Adenomatous Polyposis
Procedure: adding diverting ileostomy
Procedure: omitting diverting ileostomy

Study Type: Interventional

Resource links provided by NLM:

Further study details as provided by Mansoura University:

Arms Assigned Interventions
Active Comparator: stapled ileoanal pouch without diverting ileostomy Procedure: omitting diverting ileostomy
Placebo Comparator: stapled ileoanal pouch with diverting ileostomy Procedure: adding diverting ileostomy


Genders Eligible for Study:   Both

Inclusion Criteria:

  • patients having total proctocolectomy with ileal pouch anal anastomosis.

Exclusion Criteria:

  • hypoalbuminemia
  • prolonged steroid use
  • anemia
  • anastomosis under tension
  • leak with air test
  • bleeding
  • poor vascular supply of anastomosis
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No Contacts or Locations Provided
  More Information Identifier: NCT01173250     History of Changes
Other Study ID Numbers: 251068 
Study First Received: July 30, 2010
Last Updated: August 13, 2010
Health Authority: Egypt: Institutional Review Board

Keywords provided by Mansoura University:
total proctocolectomy with ileal pouch anal anastomosis with and without ileostomy

Additional relevant MeSH terms:
Adenomatous Polyposis Coli
Colitis, Ulcerative
Adenomatous Polyps
Colonic Diseases
Colorectal Neoplasms
Digestive System Diseases
Digestive System Neoplasms
Gastrointestinal Diseases
Gastrointestinal Neoplasms
Genetic Diseases, Inborn
Inflammatory Bowel Diseases
Intestinal Diseases
Intestinal Neoplasms
Intestinal Polyposis
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Glandular and Epithelial
Neoplastic Syndromes, Hereditary processed this record on May 25, 2016