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Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01170481
First Posted: July 27, 2010
Last Update Posted: November 18, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Carsten Heinz, St. Franziskus Hospital
  Purpose
Assessment of optic disc morphology can be difficult in patients with uveitis and papilloedema. Therefore different optical coherence tomography (OCT) and laser scanning techniques may help to detect damage to the retinal nerve fibre layer.

Condition
Uveitis Glaucoma

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Retinal Nerve Fibre Layer in Uveitic Secondary Glaucoma

Resource links provided by NLM:


Further study details as provided by Carsten Heinz, St. Franziskus Hospital:

Primary Outcome Measures:
  • Alterations of retinal nerve fibre layer by optical coherence tomography [ Time Frame: once at study entry ]
    Baseline comparision of retinal nerve fibre layer thickness in patients with uveitis and with or without papilloedema at study entry. No follow-up examination scheduled


Enrollment: 50
Study Start Date: July 2009
Study Completion Date: April 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts
papilloedema without glaucoma
papilloedema with glaucoma
glaucoma without papilloedema

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
all patients with anterior or intermediate uveitis and papillooedema in fluoreszein angiography.
Criteria

Inclusion Criteria:

  • anterior or intermediate uveitis
  • papilloedema
  • glaucoma

Exclusion Criteria:

  • dense cataract
  • dense vitreous opacification
  • circular posterior synechiae
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01170481


Locations
Germany
Department of Ophthalmology at St.-Franziskus Hospital
Muenster, Germany, 48145
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
Study Chair: Arnd Heiligenhaus, MD Department at St. Franziskus Hospital
  More Information

Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Carsten Heinz, Head of Department, St. Franziskus Hospital
ClinicalTrials.gov Identifier: NCT01170481     History of Changes
Other Study ID Numbers: 2008-128-f-S
First Submitted: July 21, 2010
First Posted: July 27, 2010
Last Update Posted: November 18, 2015
Last Verified: November 2015

Keywords provided by Carsten Heinz, St. Franziskus Hospital:
anterior and intermediate uveitis
papilloedema

Additional relevant MeSH terms:
Glaucoma
Uveitis
Papilledema
Ocular Hypertension
Eye Diseases
Uveal Diseases
Optic Nerve Diseases
Cranial Nerve Diseases
Nervous System Diseases