Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema

This study has been completed.
Information provided by (Responsible Party):
Carsten Heinz, St. Franziskus Hospital Identifier:
First received: July 21, 2010
Last updated: November 17, 2015
Last verified: November 2015
Assessment of optic disc morphology can be difficult in patients with uveitis and papilloedema. Therefore different optical coherence tomography (OCT) and laser scanning techniques may help to detect damage to the retinal nerve fibre layer.


Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Retinal Nerve Fibre Layer in Uveitic Secondary Glaucoma

Resource links provided by NLM:

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • Alterations of retinal nerve fibre layer by optical coherence tomography [ Time Frame: once at study entry ] [ Designated as safety issue: No ]
    Baseline comparision of retinal nerve fibre layer thickness in patients with uveitis and with or without papilloedema at study entry. No follow-up examination scheduled

Enrollment: 50
Study Start Date: July 2009
Study Completion Date: April 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
papilloedema without glaucoma
papilloedema with glaucoma
glaucoma without papilloedema


Ages Eligible for Study:   18 Years to 100 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
all patients with anterior or intermediate uveitis and papillooedema in fluoreszein angiography.

Inclusion Criteria:

  • anterior or intermediate uveitis
  • papilloedema
  • glaucoma

Exclusion Criteria:

  • dense cataract
  • dense vitreous opacification
  • circular posterior synechiae
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Please refer to this study by its identifier: NCT01170481

Department of Ophthalmology at St.-Franziskus Hospital
Muenster, Germany, 48145
Sponsors and Collaborators
St. Franziskus Hospital
Study Chair: Arnd Heiligenhaus, MD Department at St. Franziskus Hospital
  More Information

Additional Information:
No publications provided

Responsible Party: Carsten Heinz, Head of Department, St. Franziskus Hospital Identifier: NCT01170481     History of Changes
Other Study ID Numbers: 2008-128-f-S
Study First Received: July 21, 2010
Last Updated: November 17, 2015
Health Authority: Germany: Ethics Commission

Keywords provided by St. Franziskus Hospital:
anterior and intermediate uveitis

Additional relevant MeSH terms:
Eye Diseases
Ocular Hypertension
Uveal Diseases processed this record on November 24, 2015