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Use of Laser Speckle to Study Post Occlusive Reactive Hyperhemia in Healthy Subjects (SpeckleShake)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01169974
First Posted: July 26, 2010
Last Update Posted: November 1, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University Hospital, Angers
  Purpose
The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.

Condition Intervention
Microcirculation Other: tourniquet ischemia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation Chez Des Sujets Volontaires Sains de l'ischémie-reperfusion cutanée

Further study details as provided by University Hospital, Angers:

Primary Outcome Measures:
  • Laser speckle [ Time Frame: with 2 minutes of ischemia ]
    Peak value of laser speckle signal


Enrollment: 41
Actual Study Start Date: February 1, 2011
Study Completion Date: December 4, 2012
Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
healthy volunteers Other: tourniquet ischemia
Recording of cutaneous blood flow on the forearm at rest before and following tourniquet ischemias of 1 , 2 & 3 minutes
Other Names:
  • Laser doppler flowmetry
  • Transcutaneous oxygen pressure
  • Near infra-red spectrometry
  • Plethysmography

Detailed Description:
Ischemia and post occlusive reactive hyperemia in the skin is tested in healthy normal subjects for tourniquet ischemias of 1, 2 & 3 minutes at rest.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
healthy volunteers
Criteria

Inclusion Criteria:

  • Healthy volunteers
  • Affiliation to the French health system

Exclusion Criteria:

  • Any disease or chronic treatment
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01169974


Locations
France
University hospital
Angers, France
Sponsors and Collaborators
University Hospital, Angers
Investigators
Principal Investigator: Guillaume Mahe University Hospital in Angers
  More Information

Responsible Party: University Hospital, Angers
ClinicalTrials.gov Identifier: NCT01169974     History of Changes
Other Study ID Numbers: CHU P 2010-18
First Submitted: July 23, 2010
First Posted: July 26, 2010
Last Update Posted: November 1, 2017
Last Verified: October 2017

Keywords provided by University Hospital, Angers:
Microcirculation
laser flowmetry
Skin
Physiology