Korea Atherosclerosis Study-3 (KAS3)

This study has been completed.
Information provided by (Responsible Party):
Soo Lim, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier:
First received: July 22, 2010
Last updated: October 24, 2013
Last verified: October 2013
Multidetector-row Computed Tomography (CT) has been introduced for use in the diagnosis of coronary heart disease. The investigators aimed to characterize coronary artery disease in subjects with cardiovascular risk or not, and in particular plaque natures depending on different status of cardiovascular risk. Especially,the investigators will evaluate the relationships between the pericardial fat and severity of stenosis as well as plaque characteristics using logistic regression models.

Cardiovascular Diseases
Cardiovascular Mortality
All-cause Mortality

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of Coronary Artery Disease With Multidetector-Row Cardiac Computed Tomography in Positive Cardiovascular Risk or Not

Resource links provided by NLM:

Further study details as provided by Seoul National University Bundang Hospital:

Primary Outcome Measures:
  • Presence of coronary artery disease [ Time Frame: 5 years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Mortality [ Time Frame: 5 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA
Biochemical paramteres including lipid, glucose, insulin, and other novel cardiometabolic factors

Enrollment: 4000
Study Start Date: February 2006
Study Completion Date: May 2013
Primary Completion Date: March 2013 (Final data collection date for primary outcome measure)
High risk group
positive cardiovascular risk group
Low risk group
negative cardiovascular risk group


Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
positive cardiovascular risks or not

Inclusion Criteria:

  • Korean capable of Multidetector-Row Cardiac Computed Tomography (MDCT)

Exclusion Criteria:

  • malignancy
  • infection
  • shock
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01168362

Korea, Republic of
Seoul National University Bundang Hospital
Seongnam, Korea, Republic of
Sponsors and Collaborators
Seoul National University Bundang Hospital
Principal Investigator: Soo Lim, MD,PHD Seoul National University Bundang Hospital
  More Information

Responsible Party: Soo Lim, Professor, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier: NCT01168362     History of Changes
Other Study ID Numbers: M10642140004-06N4214 
Study First Received: July 22, 2010
Last Updated: October 24, 2013
Health Authority: Korea: Food and Drug Administration

Keywords provided by Seoul National University Bundang Hospital:
coronary artery disease
cardiovascular risk
pericardial fat

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Coronary Disease
Myocardial Ischemia
Arterial Occlusive Diseases
Heart Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on May 26, 2016