ClinicalTrials.gov
ClinicalTrials.gov Menu

The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01167647
Recruitment Status : Completed
First Posted : July 22, 2010
Last Update Posted : March 6, 2013
Sponsor:
Information provided by (Responsible Party):
Meir Medical Center

Brief Summary:
Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined.

Condition or disease
Tuberculosis

Detailed Description:

Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined. Unnecessary bronchial cultures of bacteria may lead to over treatment in patients without clinical evidence of infections and may increase the drug resistant strains.

In areas with a high prevalence of TB, routine bronchial cultures may detect clinically unsuspected TB in an appreciable proportion of cases. However, in population with a low prevalence of TB, routine culture of bronchial aspirates may incur an unnecessary expanse and may lead to over diagnosis and over treatment of patients with non pathogenic atypical mycobacteria detected by acid-fast bacillus strains.


Study Type : Observational
Actual Enrollment : 300 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Role of Routine Bacterial Culture Including Tuberculosis During
Study Start Date : July 2010
Actual Primary Completion Date : October 2012
Actual Study Completion Date : October 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Tuberculosis
U.S. FDA Resources

Group/Cohort
bronchoscopy patients



Primary Outcome Measures :
  1. number of positive tuberculosis culture [ Time Frame: 12 months ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
All patients who will undergo a bronchoscopy examination at pulmonary department in Meir Medical Center and will sign on informed consent.
Criteria

Inclusion Criteria:

  1. patients who will undergo a bronchoscopy examination at pulmonary department in Meir Medical Center
  2. patients who will sign on informed consent. -

Exclusion Criteria:

  • 1)age under 18 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01167647


Locations
Israel
Pulmonary department, Meir Medical Center
Kfar Saba, Israel, 49100
Sponsors and Collaborators
Meir Medical Center
Investigators
Principal Investigator: David Shitrit, MD Meir Medical Center

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Meir Medical Center
ClinicalTrials.gov Identifier: NCT01167647     History of Changes
Other Study ID Numbers: MMC10-087-10.CTIL
First Posted: July 22, 2010    Key Record Dates
Last Update Posted: March 6, 2013
Last Verified: March 2012

Keywords provided by Meir Medical Center:
Tuberculosis, culture, bronchoscopy

Additional relevant MeSH terms:
Tuberculosis
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections