Characterization of Familial Myopathy and Paget Disease of Bone
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|ClinicalTrials.gov Identifier: NCT01166854|
Recruitment Status : Suspended (Pending IRB approval)
First Posted : July 21, 2010
Last Update Posted : February 25, 2019
The researcher wants to explore the genetic causes of muscle disease. The researcher is particularly interested in muscle disorders that occur in combination with diseases of bone that appear to be passed on from generation to generation.
Diffuse Optical Spectroscopy will measure the concentrations of blood, water, and lipids (fats, for example) in your tissues. This device essentially measures the color of tissues in order to determine tissue physiology (its physical and chemical processes).
|Condition or disease||Intervention/treatment|
|Muscle Disorder Bone Disorder||Device: Diffuse Optical Spectroscopy|
Diffuse Optical Spectroscopy, the technique is fast and painless and was developed at the University of California, Irvine. The Diffuse Optical Spectroscopy instrument is actively involved in research studies, but is not yet a part of routine clinical practice. The result of this study will aid similar research projects that seek to improve our understanding of how tissues work and how alterations in metabolism affect long-term health.
TheDiffuse Optical Spectroscopy measurement consists of placing a probe onto the surface of your body (calf, bicep, or head). This probe will be secured by either gentle hand pressure or fastened to your skin using clinically-approved wraps such as Coban/wrap bandages or medical adhesive tape and medical glues. Several dots will be made on your skin outlining the probe with a surgical felt tip marker. This is so we would be able to put the probe again on the same spot in case we needed to interrupt the measurement. The probe looks like a bar code scanner in a supermarket and it shines infrared light on your skin. There is no radiation involved with this light. In some cases where light signals are low, the optical detector will be placed directly onto your skin (but contained within an electronically shielded casing, and placed inside another plastic casing). (not offered during pregnancy).
|Study Type :||Observational|
|Estimated Enrollment :||25 participants|
|Official Title:||Phase 1 Study Non-invasive Use Diffuse Optical Spectroscopy Will Measure the Concentrations of Blood, Water, and Lipids (Fats, for Example) in Tissues|
|Study Start Date :||June 2010|
|Estimated Primary Completion Date :||June 2020|
|Estimated Study Completion Date :||June 2020|
Diffuse Optical Spectroscopy
Device: Diffuse Optical Spectroscopy
Diffuse Optical Spectroscopy
- muscle disease [ Time Frame: 1 week ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01166854
|United States, California|
|Beckman Laser Institute Medical clinic|
|Irvine, California, United States, 92612|
|Principal Investigator:||Virginia Kimonis, MD||Beckman Laser Institute University of California Irvine|
|Study Director:||Bruce Tromberg, PhD||Beckman Laser Institute University of California Irvine|