Genomics of Primary Sclerosing Cholangitis (PSC)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01161992|
Recruitment Status : Recruiting
First Posted : July 14, 2010
Last Update Posted : August 22, 2017
Primary Sclerosing Cholangitis (PSC) is a progressive liver disorder of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PSC.
This study is being done to investigate whether genes make people more likely to develop PSC. Discovery of these genes will help us to better understand how PSC developes and subsequently, to apply new approaches for its prevention, diagnosis and treatment.
|Condition or disease||Intervention/treatment|
|Primary Sclerosing Cholangitis (PSC)||Genetic: Genetic Analysis|
|Study Type :||Observational|
|Estimated Enrollment :||1500 participants|
|Official Title:||P.R.O.G.R.E.S.S.: PSC Resource Of Genetic Risk, Environment and Synergy Studies.|
|Study Start Date :||March 2002|
|Estimated Primary Completion Date :||December 2025|
|Estimated Study Completion Date :||December 2025|
Genetic: Genetic Analysis
- Mapping of Susceptibility Genes in Adult Chronic Cholestatic Liver Diseases
Adult chronic cholestatic liver diseases, such as Primary Sclerosing Cholangitis (PSC), are progressive liver disorders of unknown cause. Current evidence suggests that genes, the genetic material we inherit from our parents, in combination with environmental factors, likely play an important role in the development of PSC.
This study is being done to investigate whether genes (the inherited genetic material passed from parents to their children) make people more likely to develop PSC. Discovery of these proposed genes will help us to better understand how PSC progresses,
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01161992
|Contact: Erik M Schlicht C.C.R.P.||firstname.lastname@example.org|
|United States, Minnesota|
|Rochester, Minnesota, United States, 55901|
|Contact: Erik M Schlicht 507-284-4312 email@example.com|
|Principal Investigator: Konstantinos N Lazaridis, M.D.|
|Principal Investigator:||Konstantinos N Lazaridis, M.D.||Mayo Clinic|