PD-1/PD-L1 Pathway Study on Septic Patients
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|ClinicalTrials.gov Identifier: NCT01161745|
Recruitment Status : Completed
First Posted : July 14, 2010
Last Update Posted : July 14, 2010
|Condition or disease|
First, we will detect PD-L1 expression on PBMC of septic patients and healthy controls.
Second, blockade of PD-1/PD-L1 pathway in vitro and stimulate with some biomolecules and then analyze the PBMC function and apoptosis by flow cytometry.
Then, compare with healthy controls and find the differences.
|Study Type :||Observational|
|Actual Enrollment :||39 participants|
|Observational Model:||Case Control|
|Official Title:||PD-1/PD-L1 Pathway in T Lymphocyte Apoptosis and Monocyte Dysfunction in Septic Patients|
|Study Start Date :||December 2008|
|Actual Primary Completion Date :||February 2010|
|Actual Study Completion Date :||April 2010|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01161745
|Principal Investigator:||Xiao-ming Deng, doctor||Changhai Hospital, the Second Military Medical University|