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Breathing and Bones Initiative

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ClinicalTrials.gov Identifier: NCT01161680
Recruitment Status : Completed
First Posted : July 13, 2010
Last Update Posted : April 16, 2015
Information provided by (Responsible Party):
University of British Columbia

Brief Summary:
This project will examine the current diagnosis and treatment of bone health in patients with obstructive airway disease. Patients will be referred to The Osteoporosis Centre of BC (OCBC) by their respirologist to be assessed for osteoporosis including Dual Energy Xray Absorptiometry (DXA) scan. Previous chest xrays and will be accessed and examined for vertebral fractures, diagnostic of osteoporosis. The lung and bone data will be entered into a database. This will allow us to explore the relationship of lung disease parameters to osteoporosis predictors, eventually determining a respirology patient population who are at high risk of fracture. Longitudinal evaluation of bone health and its relationship to respiratory parameters over time will be explored by follow-up evaluations at 12 and 24 months.

Condition or disease
Osteoporosis Obstructive Lung Disease

  Show Detailed Description

Study Type : Observational
Actual Enrollment : 30 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: A Prospective Baseline Assessment of the Risk of Osteoporosis in Patients With Chronic Obstructive Lung Disease and Outcomes After 2 Years; a Pilot Study
Study Start Date : July 2010
Primary Completion Date : September 2011
Study Completion Date : May 2012

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Primary Outcome Measures :
  1. To determine the prevalence of osteoporosis in the respiratory disease population, as determined by bone density and fragility fracture.

Secondary Outcome Measures :
  1. To associate osteoporosis with severity of pulmonary disease in respirology disease patients.

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Ages Eligible for Study:   65 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients will be drawn from specified respirology clinics: The Lung Centre (VCH) and The Pacific Lung Centre (PHC)

Inclusion Criteria:

  • men and women over 65 years of age with obstructive airway disease being seen by a respirologist in their clinical practices

Exclusion Criteria:

  • less than 65 years of age
  • patient has had bone density scan within the last 2 years
  • patient is currently being treated for osteoporosis (alendronate, risedronate, zoledronate, etidronate, clodronate, raloxifene, calcitonin, estrogen)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01161680

Canada, British Columbia
The Osteoporosis Centre of BC (Bone Consultaton and Bone Mineral Density)
Vancouver, British Columbia, Canada, V5H 3X8
The Lung Centre, Vancouver Coastal Health, 7th Floor 2775 Laurel Street
Vancouver, British Columbia, Canada, V5Z 1M9
The Pacific Lung Centre, Providence Health Care
Vancouver, British Columbia, Canada, V6Z 1Y6
Sponsors and Collaborators
University of British Columbia
Principal Investigator: Mark FitzGerald, MD University of British Columbia


Responsible Party: University of British Columbia
ClinicalTrials.gov Identifier: NCT01161680     History of Changes
Other Study ID Numbers: H10-00983
First Posted: July 13, 2010    Key Record Dates
Last Update Posted: April 16, 2015
Last Verified: April 2015

Keywords provided by University of British Columbia:
Cross sectional and Longitudinal Observational study

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases
Respiratory Tract Diseases