Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition
The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality.
The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition|
- Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA) [ Time Frame: 30 minutes ] [ Designated as safety issue: No ][The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score <17).
- All-cause mortality [ Time Frame: All-cause mortality was analyzed after median 3.5 years. ] [ Designated as safety issue: No ]Survival was calculated from the date of the MNA screening to the date of death.
- Cause-specific mortality [ Time Frame: Cause-specific mortality was analyzed after median 4.7 years. ] [ Designated as safety issue: No ]Survival was calculated from the date of the MNA screening to the date of cause-specific death.
|Study Start Date:||March 2008|
|Study Completion Date:||May 2009|
|Primary Completion Date:||May 2009 (Final data collection date for primary outcome measure)|
The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01161342
|Principal Investigator:||Leif Bergkvist, Professor||The Center for Clinical research, the County Council of Vestmanland/Uppsala University, Sweden|