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Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

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ClinicalTrials.gov Identifier: NCT01161342
Recruitment Status : Completed
First Posted : July 13, 2010
Last Update Posted : August 26, 2015
Sponsor:
Collaborator:
Information provided by (Responsible Party):

Study Description
Brief Summary:

The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality.

The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.


Condition or disease
Malnutrition

Detailed Description:
The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.

Study Design

Study Type : Observational
Actual Enrollment : 1771 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition
Study Start Date : March 2008
Primary Completion Date : May 2009
Study Completion Date : May 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Malnutrition
U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Primary Outcome Measures :
  1. Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA) [ Time Frame: 30 minutes ]
    [The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score <17).

  2. All-cause mortality [ Time Frame: All-cause mortality was analyzed after median 3.5 years. ]
    Survival was calculated from the date of the MNA screening to the date of death.

  3. Cause-specific mortality [ Time Frame: Cause-specific mortality was analyzed after median 4.7 years. ]
    Survival was calculated from the date of the MNA screening to the date of cause-specific death.


Eligibility Criteria

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Ages Eligible for Study:   65 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
The included sample comprised 1771 patients 65 years and older, consecutively admitted during fifteen months to two internal medicine wards (n = 706), two surgical wards (n = 681), and one orthopaedic ward (n = 384) at the Central hospital in Västerås, Sweden.
Criteria

Inclusion Criteria:

  • Patients 65 years or older

Exclusion Criteria:

  • unable to communicate and no relative could anwer the questions (n = 356)
  • receiving palliative care (n = 44)
  • impossible to measure height or weight (n = 22)
  • miscellanious (n = 71)
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01161342


Sponsors and Collaborators
Uppsala University
Ministry of Health and Social Affairs, Sweden
Investigators
Principal Investigator: Leif Bergkvist, Professor The Center for Clinical research, the County Council of Vestmanland/Uppsala University, Sweden
More Information

Responsible Party: Lisa Söderström, Med.lic., Uppsala University
ClinicalTrials.gov Identifier: NCT01161342     History of Changes
Other Study ID Numbers: LTV-1211142
First Posted: July 13, 2010    Key Record Dates
Last Update Posted: August 26, 2015
Last Verified: May 2011

Keywords provided by Lisa Söderström, Uppsala University:
Malnutrition
Aged
Aged 80 and over
Prevalence
Mortality

Additional relevant MeSH terms:
Malnutrition
Nutrition Disorders