Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

This study has been completed.
Ministry of Health and Social Affairs, Sweden
Information provided by (Responsible Party):
Lisa Söderström, Uppsala University Identifier:
First received: July 12, 2010
Last updated: August 25, 2015
Last verified: May 2011

The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality.

The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

Resource links provided by NLM:

Further study details as provided by Uppsala University:

Primary Outcome Measures:
  • Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA) [ Time Frame: 30 minutes ]
    [The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score <17).

  • All-cause mortality [ Time Frame: All-cause mortality was analyzed after median 3.5 years. ]
    Survival was calculated from the date of the MNA screening to the date of death.

  • Cause-specific mortality [ Time Frame: Cause-specific mortality was analyzed after median 4.7 years. ]
    Survival was calculated from the date of the MNA screening to the date of cause-specific death.

Enrollment: 1771
Study Start Date: March 2008
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Detailed Description:
The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.

Ages Eligible for Study:   65 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
The included sample comprised 1771 patients 65 years and older, consecutively admitted during fifteen months to two internal medicine wards (n = 706), two surgical wards (n = 681), and one orthopaedic ward (n = 384) at the Central hospital in Västerås, Sweden.

Inclusion Criteria:

  • Patients 65 years or older

Exclusion Criteria:

  • unable to communicate and no relative could anwer the questions (n = 356)
  • receiving palliative care (n = 44)
  • impossible to measure height or weight (n = 22)
  • miscellanious (n = 71)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01161342

Sponsors and Collaborators
Uppsala University
Ministry of Health and Social Affairs, Sweden
Principal Investigator: Leif Bergkvist, Professor The Center for Clinical research, the County Council of Vestmanland/Uppsala University, Sweden
  More Information

Responsible Party: Lisa Söderström, Med.lic., Uppsala University Identifier: NCT01161342     History of Changes
Other Study ID Numbers: LTV-1211142
Study First Received: July 12, 2010
Last Updated: August 25, 2015

Keywords provided by Uppsala University:
Aged 80 and over

Additional relevant MeSH terms:
Nutrition Disorders processed this record on April 28, 2017