Change of Body Composition After Kidney Transplantation in Korea

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01157884
Recruitment Status : Completed
First Posted : July 7, 2010
Last Update Posted : January 5, 2012
Information provided by (Responsible Party):
Yon Su Kim, Seoul National University Hospital

Brief Summary:

The graft survival in kidney transplantation has been improving after the introduction of new immunosuppressive agents. Therefore, other complications after transplantation are concerned; one of those is obesity. Several factors are attributable to obesity in kidney transplant recipients.

The body composition such as fat mass and lean mass is important concept in overweight patients. Some studies have been conducted on the change of body composition in kidney transplants. However, all of them are studied among Caucasians or using dual energy X-ray absorptiometry (DEXA).

In this study, the investigators plan to study the body composition among Asian kidney transplant recipients using the bioelectrical impedance analysis (BIA).

Condition or disease
Kidney Transplantation

Study Type : Observational
Actual Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : September 2009
Actual Primary Completion Date : August 2011
Actual Study Completion Date : September 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Kidney Transplantation

Primary Outcome Measures :
  1. change of body composition [ Time Frame: 2 weeks, 1/3/6/9/12 months after transplantation ]
    fat mass, lean mass

Secondary Outcome Measures :
  1. weight, waist circumference [ Time Frame: 2 weeks, 1/3/6/9/12 months after transplantation ]
  2. cholesterol, CRP [ Time Frame: 2 weeks, 1/3/6/9/12 months after transplantation ]

Biospecimen Retention:   None Retained
serum: total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, C-reactive protein (CRP)

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Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
recieved kidney transplantation in the Seoul National University Hospital

Inclusion Criteria:

  • aged 20 years and over

Exclusion Criteria:

  • history of previous transplantation
  • co-transplantation with other organs
  • neuropsychological problem with diet (such as anorexia nervosa, bulimia)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01157884

Korea, Republic of
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
Study Chair: Yon Su Kim, M.D., Ph.D. Seoul National University Hospital

Responsible Party: Yon Su Kim, Doctor, Seoul National University Hospital Identifier: NCT01157884     History of Changes
Other Study ID Numbers: SNUH-001-YH
First Posted: July 7, 2010    Key Record Dates
Last Update Posted: January 5, 2012
Last Verified: January 2012

Keywords provided by Yon Su Kim, Seoul National University Hospital:
body composition
kidney transplantation