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PET-CT Based Radiotherapy in Esophageal Cancer Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01156831
First Posted: July 5, 2010
Last Update Posted: December 8, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Maastricht Radiation Oncology
  Purpose
The purpose of this study is to determine the locoregional control in PET/CT based radiotherapy treatment planning in the treatment of esophageal cancer patients.

Condition
Esophageal Neoplasms

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Consequences of Positron-Emission-Tomography/Computed Tomography (PET/CT) Based Radiotherapy Treatment Planning for Clinical Outcome in Esophageal Cancer Patients

Resource links provided by NLM:


Further study details as provided by Maastricht Radiation Oncology:

Primary Outcome Measures:
  • Locoregional control [ Time Frame: 2 years and 5 years ]

Secondary Outcome Measures:
  • Overall Survival [ Time Frame: 2 years and 5 years ]
  • Disease Free survival [ Time Frame: 2 years and 5 years ]
  • Tumor regression grade [ Time Frame: At the time of surgery ]
    Tumor regression grade at time of surgery evaluated by pathologist.


Enrollment: 115
Study Start Date: November 2007
Study Completion Date: May 2013
Primary Completion Date: May 2011 (Final data collection date for primary outcome measure)
Detailed Description:
The purpose of this study is to determine the locoregional control in PET/CT based radiotherapy treatment planning in the treatment of esophageal cancer patients
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Primary Care Clinic
Criteria

Inclusion Criteria:

  • Histologically proven adenocarcinoma or squamous cell carcinoma of the esophagus
  • Local curable disease able to undergo Chemoradiotherapy.

Exclusion Criteria:

  • Metastasized disease.
  • Previous or concurrent malignancies.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01156831


Locations
Netherlands
Atrium Hospital
Heerlen, Netherlands
University Medical Center
Maastricht, Netherlands
St. Laurentius Hospital
Roermond, Netherlands
Maasland Hospital
Sittard, Netherlands
St. Jansgasthuis
Weert, Netherlands
Sponsors and Collaborators
Maastricht Radiation Oncology
Investigators
Principal Investigator: Guido Lammering, MD PhD Radiation Oncology, Maastro Clinic
Principal Investigator: Meindert Sosef, MD PhD Atrium Hospital Heerlen
  More Information

Responsible Party: Maastricht Radiation Oncology
ClinicalTrials.gov Identifier: NCT01156831     History of Changes
Other Study ID Numbers: 09-18-12/08
First Submitted: July 2, 2010
First Posted: July 5, 2010
Last Update Posted: December 8, 2014
Last Verified: December 2014

Keywords provided by Maastricht Radiation Oncology:
Esophageal cancer
PET-CT planning

Additional relevant MeSH terms:
Esophageal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Neoplasms
Head and Neck Neoplasms
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases