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Investigation of Dysregulated Signaling in MPD Via Multiparameter Phospho-specific Flow Cytometry

This study has been terminated.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01144780
First Posted: June 16, 2010
Last Update Posted: July 1, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Stanford University
  Purpose
The objective of this study is to better understand the underlying pathogenetic mechanisms of MPDs. We will collect peripheral blood samples from MPD patients and utilize multiparameter phospho-specific flow cytometry to investigate dysregulated signaling in blood cells from these patients. This will provide deeper insights into the pathogenesis of MPDs and may lead to the identification of novel targets for therapeutic intervention.

Condition
Myeloproliferative Disorders Myeloproliferative Disorders (MPD)

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Investigation of Dysregulated Signaling in Myeloproliferative Disorders Via Multiparameter Phospho-specific Flow Cytometry

Resource links provided by NLM:


Further study details as provided by Stanford University:

Biospecimen Retention:   Samples Without DNA
blood and bone marrow

Enrollment: 10
Study Start Date: September 2009
Study Completion Date: June 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Any patient who carries a diagnosis of a myeloproliferative disorder (MPD).
Criteria

Inclusion Criteria:Any patient who carries a diagnosis of a myeloproliferative disorder (MPD).

Exclusion Criteria:Any patient who is not willing to give consent.

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01144780


Locations
United States, California
Stanford University School of Medicine
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Investigators
Principal Investigator: Jason Robert Gotlib Stanford University
Principal Investigator: Stephen Tracy Oh Stanford University
  More Information

Responsible Party: Stanford University
ClinicalTrials.gov Identifier: NCT01144780     History of Changes
Other Study ID Numbers: HEMMPD0011
SU-07092009-3060 ( Other Identifier: Stanford )
First Submitted: June 14, 2010
First Posted: June 16, 2010
Last Update Posted: July 1, 2016
Last Verified: June 2016

Additional relevant MeSH terms:
Disease
Myeloproliferative Disorders
Pathologic Processes
Bone Marrow Diseases
Hematologic Diseases