Internet-Based Clinical Information and Blood Sample Collection From Patients With Non-Small Cell Lung Cancer Who Never Smoked Cigarettes
RATIONALE: Gathering health information about patients with non-small cell lung cancer who never smoked cigarettes may help doctors learn more about the disease. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about cancer and identify biomarkers related to cancer.
PURPOSE: This research study is studying internet-based clinical information and blood sample collection from patients with non-small cell lung cancer who never smoked cigarettes.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Survey and Blood Sample Collection for Patients With Lung Cancer Who Never Smoked Cigarettes|
- Feasibility of an internet-based protocol to collect clinical information and biological specimens [ Time Frame: Six months following collection of final patient data and biospecimen ] [ Designated as safety issue: No ]
- Identification of alleles that predispose to lung cancer via genome-wide association studies [ Time Frame: one year following collection of final patient data and biospecimen ] [ Designated as safety issue: No ]
|Study Start Date:||July 2009|
|Study Completion Date:||September 2012|
|Primary Completion Date:||August 2012 (Final data collection date for primary outcome measure)|
|Never-smokers with lung cancer||
Other: internet-based protocol and physician referral
collection and review, dna and lab biomarker analysis, gene mapping
- To assess the feasibility of an internet-based protocol to collect clinical information and biological specimens from 2,000 never smokers with non-small cell lung cancer.
- To perform genome-wide association studies to identify alleles that predispose to lung cancer in patients that never smoked cigarettes.
Patients complete an internet-based questionnaire using the REDCap (Research Electronic Data Capture) survey to determine eligibility. The survey consists of a detailed smoking questionnaire and questions to collect information regarding diagnosis, sex, age, ethnicity, treatment history, and any history of previous malignancies. Blood samples are then collected from eligible patients for DNA and other laboratory analyses. Patients' pathology reports are also reviewed.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01141218
|United States, Tennessee|
|Vanderbilt-Ingram Cancer Center|
|Nashville, Tennessee, United States, 37232|
|Principal Investigator:||William Pao, MD, PhD||Vanderbilt-Ingram Cancer Center|