Internet-Based Clinical Information and Blood Sample Collection From Patients With Non-Small Cell Lung Cancer Who Never Smoked Cigarettes
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01141218|
Recruitment Status : Terminated (slow accrual)
First Posted : June 10, 2010
Last Update Posted : April 25, 2017
RATIONALE: Gathering health information about patients with non-small cell lung cancer who never smoked cigarettes may help doctors learn more about the disease. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about cancer and identify biomarkers related to cancer.
PURPOSE: This research study is studying internet-based clinical information and blood sample collection from patients with non-small cell lung cancer who never smoked cigarettes.
|Condition or disease||Intervention/treatment|
|Lung Cancer||Other: internet-based protocol and physician referral|
- To assess the feasibility of an internet-based protocol to collect clinical information and biological specimens from 2,000 never smokers with non-small cell lung cancer.
- To perform genome-wide association studies to identify alleles that predispose to lung cancer in patients that never smoked cigarettes.
Patients complete an internet-based questionnaire using the REDCap (Research Electronic Data Capture) survey to determine eligibility. The survey consists of a detailed smoking questionnaire and questions to collect information regarding diagnosis, sex, age, ethnicity, treatment history, and any history of previous malignancies. Blood samples are then collected from eligible patients for DNA and other laboratory analyses. Patients' pathology reports are also reviewed.
|Study Type :||Observational|
|Actual Enrollment :||88 participants|
|Official Title:||Survey and Blood Sample Collection for Patients With Lung Cancer Who Never Smoked Cigarettes|
|Study Start Date :||July 2009|
|Actual Primary Completion Date :||August 2012|
|Actual Study Completion Date :||September 2012|
|Never-smokers with lung cancer||
Other: internet-based protocol and physician referral
collection and review, dna and lab biomarker analysis, gene mapping
- Feasibility of an internet-based protocol to collect clinical information and biological specimens [ Time Frame: Six months following collection of final patient data and biospecimen ]
- Identification of alleles that predispose to lung cancer via genome-wide association studies [ Time Frame: one year following collection of final patient data and biospecimen ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01141218
|United States, Tennessee|
|Vanderbilt-Ingram Cancer Center|
|Nashville, Tennessee, United States, 37232|
|Principal Investigator:||William Pao, MD, PhD||Vanderbilt-Ingram Cancer Center|