Control of MRSA in Nursing Homes: Decolonization vs Standard Precautions
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|ClinicalTrials.gov Identifier: NCT01138462|
Recruitment Status : Completed
First Posted : June 7, 2010
Last Update Posted : May 23, 2014
|Condition or disease||Intervention/treatment||Phase|
|Methicillin-Resistant Staphylococcus Aureus||Other: intervention||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||157 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Universal Screening and Decolonization vs Standard Precautions for Control of Methicillin-resistant Staphylococcus Aureus (MRSA) in Nursing Homes: a Cluster, Randomised Controlled Study.|
|Study Start Date :||June 2010|
|Actual Primary Completion Date :||December 2011|
|Actual Study Completion Date :||December 2011|
No Intervention: Standard Precautions
control arm, standards precautions for all residents living in the nursing home of control arm, including MRSA carriers
Intervention arm, standards precautions for all residents living in nursing homes of intervention arm, and topical decolonization for MRSA carriers, including environmental disinfection
5 days topical decolonisation including nasal mupirocin tid, chlorhexidine mouth wash tid, chlorhexidine body wash once daily.
Daily direct resident's environmental disinfection during decolonisation.
Other Name: topical MRSA decolonisation and environmental disinfection
- To determine the change in prevalence of MRSA carriage among residents of each Nursing homes group at the end of the one study year [ Time Frame: 1 year ]in each control and intervention nursing home: MRSA screening of all residents of nursing homes of Canton Vaud, at baseline and 1 year later, in order to compare MRSA prevalence changes at nursing homes levels
- To determine the effectiveness of the reinforced strategy to prevent MRSA infection, compared to the standard strategy [ Time Frame: 1 year ]In a subpopulation of all nursing homes residents (10% of the whole population), recording of all microbiologically documented MRSA infection, according to nosocomial infection definitions of the Center of Diseases Control (CDC) of Atlanta.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01138462
|all nursing homes of canton Vaud|
|Canton de Vaud, Canton Vaud, Switzerland|
|Study Director:||Giorgio Zanetti, MD||University Hospital of Lausanne, Switzerland|