Study of Episodic Breathlessness in Patients With Lung Cancer or Other Advanced Disease
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|ClinicalTrials.gov Identifier: NCT01138358|
Recruitment Status : Completed
First Posted : June 7, 2010
Last Update Posted : August 26, 2013
RATIONALE: Gathering information about experiences of episodic breathlessness in patients with advanced disease may help doctors learn more about the disease.
PURPOSE: This clinical trial is studying experiences of episodic breathlessness in patients with lung cancer or other advanced disease.
|Condition or disease||Intervention/treatment|
|Dyspnea Lung Cancer Metastatic Cancer||Other: medical chart review Other: study of socioeconomic and demographic variables Other: survey administration Procedure: quality-of-life assessment|
- To explore the experiences of episodic breathlessness in patients with advanced disease (i.e., primary and secondary lung cancer, chronic obstructive pulmonary disease [COPD], chronic heart failure [CHF], and motor neuron disease [MND]).
- To explore the impact of episodic breathlessness on daily living.
- To explore the individual coping strategies to reduce burden of episodic breathlessness.
OUTLINE: This is a multicenter study.
Patients undergo 1 to 2 interviews to collect data on experiences of breathlessness (in general, at rest, and on exertion including symptom description, interpretation, and meaning); experiences of episodic breathlessness (EB) (at rest and on exertion including symptom description, interpretation, meaning, and definition); trajectory/course of EB (onset/relief, time, and severity) and different types/trajectories of EB; impact of EB (burden, emotional reaction [panic and fear], care burden, and dependencies); triggers of EB (causes, situation, and settings) and predictability of EB; management of EB (coping strategies, non-pharmacological and pharmacological management [including different applications], worsen/relief, role of care in coping, and emotional/behavior strategies; views on and experiences with services/professionals in management of EB and response to professional advice; and attitudes towards the future, course of the disease, and awareness of prognosis. At the end of the interview, the patient will be asked to draw a figure that illustrates the trajectory of the episode. After the interview, a debriefing will be carried out to give the patient the chance to express worries, potential harm, or any comments about the interview. In addition to the interviews, further information will be collected including demographics, diagnosis and co-morbidities, current pharmacological and non-pharmacological treatments (medical history), functional status (Karnofsky), and breathlessness characteristics (e.g., intensity, frequency, and duration). The interviews will be tape-recorded, transcribed verbatim, and analyzed concurrently using Framework Approach.
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Experiences of Episodic Breathlessness (EB) in Patients With Advanced Disease|
|Study Start Date :||January 2010|
|Actual Primary Completion Date :||August 2010|
|Actual Study Completion Date :||October 2012|
- Experiences of episodic breathlessness
- Impact of episodic breathlessness on daily living
- Individual coping strategies to reduce burden of episodic breathlessness
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01138358
|King's College Hospital|
|London, England, United Kingdom, SE5 9RJ|
|Principal Investigator:||Steffen Simon, MD, MSC||King's College Hospital NHS Trust|