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The Impact of Vitamin D on Tuberculosis Among Koreans

This study has been completed.
Information provided by (Responsible Party):
Jae-Joon Yim, Seoul National University Hospital Identifier:
First received: June 3, 2010
Last updated: January 3, 2014
Last verified: January 2014
Vitamin D has been regarded to be beneficial to tuberculosis (TB) patients. The aim of this study is to elucidate the role of vitamin D deficiency in development and treatment outcomes among Korean TB patients. Furthermore, the impact of genotypes of vitamin D receptor gene on TB development will also be evaluated.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Impact of Vitamin D Level and Single Nucleotide Polymorphisms of Vitamin D Receptor Gene on the Development and Treatment Response of Tuberculosis

Resource links provided by NLM:

Further study details as provided by Jae-Joon Yim, Seoul National University Hospital:

Primary Outcome Measures:
  • Prevalence of Vitamin D Deficiency [ Time Frame: At enrollment ]
  • Median 25-OHD Level [ Time Frame: August 2010 to March 2011 ]

Biospecimen Retention:   Samples With DNA
Serums for vitamin D measurement DNA for genotyping of vitamin D receptor gene

Enrollment: 203
Study Start Date: January 2010
Study Completion Date: April 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Patients with TB
People without TB


Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients diagnosed and treated as having a TB in Seoul National University Hospital

Inclusion Criteria:

  • older than 19 years
  • diagnosed and treated having a tuberculosis

Exclusion Criteria:

  • positive HIV antibody
  Contacts and Locations
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Please refer to this study by its identifier: NCT01137370

Korea, Republic of
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
  More Information

Responsible Party: Jae-Joon Yim, Professor, Seoul National University Hospital Identifier: NCT01137370     History of Changes
Other Study ID Numbers: H-0911-066-301
Study First Received: June 3, 2010
Results First Received: January 3, 2014
Last Updated: January 3, 2014

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections
Vitamin D
Growth Substances
Physiological Effects of Drugs
Bone Density Conservation Agents processed this record on September 21, 2017