Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion
The developments of solar lentigine and melasma are due to mutations in keratinocytes that drive the production and transfer of pigment from melanocytes to keratinocytes.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion.|
- Characterization and classification of lentigines and melasma [ Time Frame: 3 years ] [ Designated as safety issue: No ]
Characterize and classify lentigines and mealsma from a clinical and physiological point of view. This will better understand the cellular processes leading to the development of lentigines (also referred to as Senile or Solar Lentigo).
Proper characterization and classification of lentigines and melasma would facilitate the development of models to study and find solutions to treat these lesions.
|Study Start Date:||June 2008|
|Estimated Study Completion Date:||May 2015|
|Estimated Primary Completion Date:||May 2015 (Final data collection date for primary outcome measure)|
Subjects with hyper-pigmented spots
Subjects age 21 to 80 year old, who have elected to undergo a plastic surgery will be enrolled. Subjects will be from Chinese, Malay, Indian or Caucasian ancestry. Subjects will be female or male with a hyper-pigmented spots.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01136629
|Contact: Thiam Chye Lim, MDemail@example.com|
|Contact: Eileen Hingfirstname.lastname@example.org|
|National University Hospital, Singapore||Recruiting|
|Singapore, Singapore, 119074|
|Contact: Thiam Chye Lim, MD 65-67722022 email@example.com|
|Contact: Eileen Hing 65-67722276 firstname.lastname@example.org|
|Principal Investigator: Thiam Chye Lim, MD|
|Principal Investigator:||Thiam Chye Lim, MD||National University Hospital, Singapore|