DM1 Heart Registry - DM1 Respiratory Registry (DM1-Heart-R)
|ClinicalTrials.gov Identifier: NCT01136330|
Recruitment Status : Completed
First Posted : June 3, 2010
Last Update Posted : February 20, 2012
Myotonic dystrophy type 1 (DM1) is the most frequent neuromuscular disease in adults. DM1 patients have an impaired prognosis (mean age of death <60 years) due to cardiac and respiratory complications.
Our primary objective was to identify cardiac and respiratory prognostic factors in DM1.
|Condition or disease|
- Patients with genetically proven DM1 who were admitted in Pitié Salpêtrière Hospital from 2000 and 2010 will be identified. These patients systematically underwent neurological, cardiac and respiratory investigations.
- Baseline medical and genetic information will be entered in a dedicated database, including cardiac and respiratory investigations.
- The occurence of severe cardiac and respiratory adverse events will also be collected.
- Statistical analysis will be performed to look for correlations between baseline patient characteristics and cardiac or respiratory adverse events during follow up.
|Study Type :||Observational|
|Actual Enrollment :||914 participants|
|Official Title:||Cardiac and Respiratory Prognostic Factors in Patients With Myotonic Dystrophy Type 1|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||September 2011|
|Actual Study Completion Date :||September 2011|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01136330
|Pitié Salpêtrière Hospital|
|Paris, Ile de France, France, 75013|
|Study Director:||Denis Duboc, MD,PhD||APHP|