Swallowing Training in Parkinson`s Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01131494
Recruitment Status : Completed
First Posted : May 27, 2010
Results First Posted : November 8, 2011
Last Update Posted : November 8, 2011
Information provided by (Responsible Party):
Natalie Argolo Pereira Ponte, Federal University of Bahia

Brief Summary:
Dysphagia in Parkinson's disease(PD) is common and its presence is related to motor and sensory abnormalities, and incoordination between swallowing and breathing. Despite harming as respiratory infections and increased risk of death, treatment of this condition remains uncertain. This study aims to evaluate the effect of oral motor exercises on the swallowing dynamics and quality of life of dysphagic Parkinson's disease patients. This study is an open trial, self-paired and blinded to the examiner. The participants will perform oropharyngeal exercises for five weeks and will be evaluated before and after intervention by swallowing videofluoroscopy and questionnaires about quality of life in dysphagia (SWAL-QOL).

Condition or disease Intervention/treatment Phase
Parkinson's Disease Deglutition Disorders Voice Disorders Other: Motor exercises for swallowing, breathing and phonation Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 17 participants
Intervention Model: Single Group Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Dysphagia Therapy for Parkinson`s Disease: the Role of the Oral Motor Exercises
Study Start Date : March 2009
Actual Primary Completion Date : October 2010
Actual Study Completion Date : December 2010

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: Swallowing exercises Other: Motor exercises for swallowing, breathing and phonation
This exercises aimed to increase strength and range of motion of mouth, larynx and pharynx structures. All patients made sustained vowel phonation of /a/, pushing plosive phonemes /pa/, /ta/, /ka/ in a forceful manner, suction of wet gauze, swallowing with tongue hold and modified supraglottic maneuver, in ten repetitions, ascending and descending gliding phonation of vowel /a/ and /u/, five repetitions of each vowel, and tongue rotation in oral vestibule, 3 series of 5 repetitions to each side. Patients underwent oral motor exercises twice a day, five days a week, for five weeks.

Primary Outcome Measures :
  1. Oropharyngeal Swallowing Score [ Time Frame: five weeks ]
    Based on videofluoroscopy, were awarded points for the swallowing events according to their clinical relevance. The sum of these points results in the OSP (Oropharyngeal Swallowing Score), so that higher scores signify greater impairment in swallowing. OSP-score range from 0 to 243.5. This tool is being validated for that group.

Secondary Outcome Measures :
  1. Quality of Life [ Time Frame: five weeks ]
    Measured by the Swal-qol (Quality of life in Swallowing disorders). In this questionnaire the score range from 0 to 100 and higher scores is better quality of life.

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinical diagnosis of Parkinson disease
  • Complaint of dysphagia

Exclusion Criteria:

  • Hoehn and Yahr stage 5
  • Other neurological conditions
  • Therapy for swallowing in the last 3 months
  • Cognitive disorders
  • Psychiatric disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01131494

Federal University of Bahia
Salvador, Bahia, Brazil, 40110-170
Sponsors and Collaborators
Federal University of Bahia
Study Chair: Ana Caline Nóbrega, PhD Federal University of Bahia

Responsible Party: Natalie Argolo Pereira Ponte, PhD Student, Federal University of Bahia Identifier: NCT01131494     History of Changes
Other Study ID Numbers: 249/2008
First Posted: May 27, 2010    Key Record Dates
Results First Posted: November 8, 2011
Last Update Posted: November 8, 2011
Last Verified: October 2011

Keywords provided by Natalie Argolo Pereira Ponte, Federal University of Bahia:
Parkinson's disease

Additional relevant MeSH terms:
Voice Disorders
Parkinson Disease
Deglutition Disorders
Pathologic Processes
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Pharyngeal Diseases
Otorhinolaryngologic Diseases
Laryngeal Diseases
Respiratory Tract Diseases
Neurologic Manifestations
Signs and Symptoms