Immunological Change and the Single Nucleotide Polymorphism (SNP) in Children With Irritable Bowel Syndrome (IBS)
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ClinicalTrials.gov Identifier: NCT01131442
Recruitment Status : Unknown
Verified May 2010 by Chang Gung Memorial Hospital. Recruitment status was: Recruiting
Currently, the pathophysiology of Irritable bowel syndrome( IBS) remains unclear . The purpose of this study is want to investigate the immunological changes in the children with IBS.
Condition or disease
Irritable Bowel SyndromeChildren
Irritable bowel syndrome (IBS) is a highly prevalent functional gastrointestinal disorder.Many children suffered from this disease and had impact on their daily life. However, the underlying pathophysiologic mechanisms remain to be elucidate. Dysregulation of the gut immune system is considered an important pathophysiology. We want to investigate the immunological changes in the IBS children.
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Ages Eligible for Study:
5 Years to 18 Years (Child, Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
out patient clinics in the hospital
(5-18y/o) with IBS,
All patients had chronic or relapsing symptoms of IBS consistent with the ROME II criteria
A history of psychologic disorders, probiotics, anti-inflammatory, analgesic, or immunosuppressive medication (nonsteroidal anti-inflammatory drugs, steroids) within the past 3 months were excluded