Fetal Programming of Obesity

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Arkansas Children's Hospital Research Institute
ClinicalTrials.gov Identifier:
First received: May 25, 2010
Last updated: September 9, 2015
Last verified: September 2015
The overall goal of this project is to understand how a mother's health at conception may influence her child's growth and development.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Further study details as provided by Arkansas Children's Hospital Research Institute:

Primary Outcome Measures:
  • Child body composition [ Time Frame: 3 years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Child growth and development [ Time Frame: 3 years ] [ Designated as safety issue: No ]
  • Child metabolism [ Time Frame: 3 years ] [ Designated as safety issue: No ]
  • Child dietary intake [ Time Frame: 3 years ] [ Designated as safety issue: No ]
  • Placenta gene expression [ Time Frame: 9 months ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA
Blood, urine, stool, placenta, cord blood and umbilical cord may be collected from study participants.

Estimated Enrollment: 320
Study Start Date: April 2010
Estimated Study Completion Date: August 2018
Estimated Primary Completion Date: September 2017 (Final data collection date for primary outcome measure)
Pregnant women


Ages Eligible for Study:   21 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy women

Inclusion Criteria:

  • healthy
  • 21 years of age or older
  • second pregnancy, singleton
  • conceived without fertility treatments

Exclusion Criteria:

  • Preexisting medical conditions
  • Sexually transmitted diseases
  • Medical complications during pregnancy
  • Medications during pregnancy known to influence fetal growth
  • Smoking, alcohol drinking
  • Excessive physical activity level which could affect the outcome of interest.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01131117

United States, Arkansas
Arkansas Children's Nutrition Center
Little Rock, Arkansas, United States, 72202
Sponsors and Collaborators
Arkansas Children's Hospital Research Institute
  More Information

No publications provided

Responsible Party: Arkansas Children's Hospital Research Institute
ClinicalTrials.gov Identifier: NCT01131117     History of Changes
Other Study ID Numbers: 110889
Study First Received: May 25, 2010
Last Updated: September 9, 2015
Health Authority: United States: Food and Drug Administration

Keywords provided by Arkansas Children's Hospital Research Institute:

ClinicalTrials.gov processed this record on November 24, 2015