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Cell Culture of Glioma Specimens for in Vitro Preclinical Studies

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2009 by Albany Medical College.
Recruitment status was:  Recruiting
Information provided by:
Albany Medical College Identifier:
First received: May 18, 2010
Last updated: June 24, 2011
Last verified: April 2009

The purpose of this study is to culture primary human brain tumor cells with the specific aims of:

  1. Develop primary cultures from human brain tumor surgical specimens
  2. Determine the genetic and molecular fingerprints of brain tumors that may have prognostic significance
  3. Delineate the mechanisms underlying oncogenesis of brain tumors.
  4. Perform in vitro assays with brain tumor derived primary cultures to assess the efficacy of novel therapeutic agents.

Brain Tumor

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Primary Cell Culture of Surgical Glioma Specimens for Invitro Preclinical Studies

Resource links provided by NLM:

Further study details as provided by Albany Medical College:

Biospecimen Retention:   Samples Without DNA
All subjects will be give permission for specimen storage by signing a separate permission on the informed consent. All specimens will be stored at a tissue bank for an unspecified amount of time.

Estimated Enrollment: 50
Study Start Date: April 2009
Estimated Study Completion Date: June 2012
Estimated Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients 18 years of age or older undergoing surgical resection for gliomas.

Inclusion Criteria:

  • Patients 18 years of age or older undergoing surgical resection for glioma

Exclusion Criteria:

  • Under 18 years of age
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01125826

Contact: Yu-Hung Kuo, MD 518 262 5088

United States, New York
Albany Medical Center Recruiting
Albany, New York, United States, 12208
Contact: Tyler Kenning, MD   
Sponsors and Collaborators
Albany Medical College
  More Information

Responsible Party: Yu-Hung Kuo, MD, Neurosciences Institute, Albany Medical College Identifier: NCT01125826     History of Changes
Other Study ID Numbers: 2536
Study First Received: May 18, 2010
Last Updated: June 24, 2011 processed this record on September 21, 2017