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The Role of Daily Disposable Contact Lenses in Ocular Allergy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01125540
Recruitment Status : Completed
First Posted : May 18, 2010
Last Update Posted : May 18, 2010
Sponsor:
Collaborator:
Information provided by:

Study Description
Brief Summary:
Patients with seasonal allergic conjunctivitis are normally advised to avoid contact lens wear when they are having symptoms. However, modern soft contact lenses which are disposed of daily offer the potential to protect and lubricate the ocular surface. This study examines this possible effect.

Condition or disease Intervention/treatment
Grass Pollen Ocular Allergy Device: Acuvue (Standard Daily Disposable Contact Lens) Device: CIBA Dailies Aquacomfort Plus (Contact Lens - enhance lubricating)

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Prevention
Official Title: The Role of Daily Disposable Contact Lenses in Ocular Allergy
Study Start Date : June 2007
Primary Completion Date : January 2010
Study Completion Date : January 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Intervention Details:
    Device: Acuvue (Standard Daily Disposable Contact Lens)
    Other Name: Acuvue
    Device: CIBA Dailies Aquacomfort Plus (Contact Lens - enhance lubricating)
    Other Name: CIBA Dailies Aquacomfort Plus

Outcome Measures

Primary Outcome Measures :
  1. Symptoms [ Time Frame: 4 hours ]
    Subjective rating of itchyness, dryness, burning, watering and discomfort

  2. Signs [ Time Frame: 4 hours ]
    Signs of bulbar, limbal and palpebtal hyperaemia and staining


Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • contact lens wearer
  • proven allergy to grass pollen

Exclusion Criteria:

  • eye disease
  • ocular medication
  • allergy medication
  • asthma
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01125540


Locations
United Kingdom
Aston University
Birmingham, West Midlands, United Kingdom, B4 7ET
Sponsors and Collaborators
Aston University
National Pollen and Aerobiology Unit, Worcester
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Prof James Wolffsohn, Aston University
ClinicalTrials.gov Identifier: NCT01125540     History of Changes
Other Study ID Numbers: Allergy02
First Posted: May 18, 2010    Key Record Dates
Last Update Posted: May 18, 2010
Last Verified: May 2010

Keywords provided by Aston University:
Allergic conjunctivitis

Additional relevant MeSH terms:
Hypersensitivity
Immune System Diseases