Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD) (Cog-RAST)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01124721
Recruitment Status : Completed
First Posted : May 17, 2010
Last Update Posted : May 31, 2017
Information provided by (Responsible Party):
University of California, Davis

Brief Summary:
Impaired WM is a central deficit in ADHD. A computerized training program, Cogmed, has been shown to increase WM capacity in children with ADHD. It is not known whether the training improves behavior associated with classroom learning, such as remaining on-task and inhibiting off- task behavior. The aim of this study is to utilize ecologically valid measures to investigate training's effect on observable ADHD behavior in conjunction with more standard measures. Subjects will be randomly assigned to a Cogmed versus an active "placebo" condition in which the tasks do not increase in difficulty level in a double-blinded fashion. The effects of the active Cogmed versus placebo computer training will be compared on measures in children with ADHD.

Condition or disease Intervention/treatment Phase
ADHD Attention Behavioral: Cognitive training Behavioral: Cognitive training-placebo Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 26 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Pilot Testing of Cognitive Training on Academic Task Performance in Children With Attention-deficit/Hyperactivity Disorder
Study Start Date : January 2008
Actual Primary Completion Date : January 2013
Actual Study Completion Date : January 2013

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: Cogmed cognitive training
Computerized working memory, attention and cognitive tasks
Behavioral: Cognitive training
Cognitive computerized training for several days per week.
Other Name: Cogmed
Active Comparator: Active placebo
Cognitive training, however the training does not increase in difficulty, or does so to a minimal degree.
Behavioral: Cognitive training-placebo
Cognitive training that only minimally increases in difficulty
Other Name: Cogmed placebo

Primary Outcome Measures :
  1. Restricted Academic Situations Task [ Time Frame: 6 weeks ]
    Assessment of on-task type behavior while doing a simulated academic task.

  2. Working memory measures [ Time Frame: 6 weeks ]
    Assess memory and working memory functioning on computer and or RA administered tests.

  3. Rating scales [ Time Frame: 6 weeks ]
    Parent and teacher ratings of behavior and attention

Secondary Outcome Measures :
  1. Fluency and attention measures [ Time Frame: 6 weeks ]
    Measures of fluency and attentional functioning.

  2. Self-control and executive functioning measures [ Time Frame: 6 weeks ]
    Attention and working memory components can affect delay discounting and self-control measures. This measure will assess for change in behavior and ratings associated with executive functioning.

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Ages Eligible for Study:   7 Years to 14 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Age range 7-14
  2. At least average academic and intellectual functioning via parent report.
  3. Must have ADHD (by parent report of previous diagnosis or per telephone screening checklist - to be confirmed via interview and ratings)
  4. Attentional, hyperactive or impulsive symptoms that interfere with functioning.

Exclusion Criteria:

  1. Diagnosis of severe mental illness for example, psychotic, bipolar or major depressive disorder, (by history)
  2. Mental retardation (by history)
  3. English is not the primary language
  4. Family does not have a computer

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01124721

United States, California
UCaliforniaDavis MIND Institute
Sacramento, California, United States, 95825
Sponsors and Collaborators
University of California, Davis
Principal Investigator: Julie Schweitzer, PhD University of California, Davis

Responsible Party: University of California, Davis Identifier: NCT01124721     History of Changes
Other Study ID Numbers: 200816598
First Posted: May 17, 2010    Key Record Dates
Last Update Posted: May 31, 2017
Last Verified: May 2017

Keywords provided by University of California, Davis:
Cognitive training

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders
Mental Disorders