Working… Menu
Trial record 1 of 1 for:    NCT01123174
Previous Study | Return to List | Next Study

Effectiveness of a Case Management Algorithm: ALGOS After a Suicide Attempt (ALGOS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01123174
Recruitment Status : Completed
First Posted : May 14, 2010
Last Update Posted : June 18, 2015
Information provided by (Responsible Party):
University Hospital, Lille

Brief Summary:

The suicidal behaviors are phenomena eminently multifactorial. It is thus always difficult to define univocal strategies of prevention of suicide repetition, during the emergency stay, i.e. almost in general population. One find 23 clinical trials in this topic in the past 25 years, and 18 are negative. The majority of the positive trials have the concern of being dissociated from an assumption of responsibility of care strictly speaking, to adopt a position "méta", nearer to the concept of "case management": how to remain in contact with the suicide attempter, without forcing it in this every day life, replacing a possible proposing, but assumption of responsibility resources reliable and quickly accessible in the event of at risk situation? Each one of these studies tests devices which seem more appropriate to such or such characteristic of this population, by retaining only simple criteria like the sex, the number of former suicide attempts, the proposal or not for an assumption of responsibility of care, the observance or not with the plan of care. Thus, it would seem interesting to combine these approaches in an algorithm entitled "ALGOS".

Main aim: To test the effectiveness of this algorithm of case management, named "ALGOS", in reducing the number of death by suicide, in terms of reduction of suicide re-attempts and the number of loss of contact patients in the ALGOS group during 6 months period, compared to a control group of suicide attempters treated as usual (i.e. primarily transmitted to the attending physician).

Secondary objectives: To evaluate, according to the method validated by Beecham in 1992, direct medico-economic impact in the year which follows the introduction of algorithm ALGOS. Reduction of the other suicidal behaviors in 6 months (reduction in the full number of suicidal repetitions in each group, evolution of the score of suicidal ideation, etc…). To evaluate the effect of the algorithm, at the 13th month. To study the possible differences within the time in terms of suicidal repetitions in the 2 groups. To propose different profiles of answers according to psychopathology, the number of suicide attempts, suicidal character, the sex,…

Methodology: Comparative simple blind prospective multicentric controlled study

Condition or disease Intervention/treatment Phase
Suicide, Attempted Behavioral: ALGOS algorithm of case management Not Applicable

Detailed Description:
Evaluations: The subjects will be included in the participating centers following a suicide attempt (SA). After checking of the criteria, information and signature of the study consent, the subjects will be randomized in one of the 2 groups (ALGOS versus Control). A fax of inclusion will be sent to the centralized research team of the Clinical Investigation Center (CIC) of Lille. All the subjects included will be then evaluated at the 6th month and 13th month after the SA, during a phone call. The final evaluation will be carried out in the current of the 13th month, so as to avoid a recontact at the time of the period birthday, too charged affectively at the majority with the patients. This phone call, personal, will be carried out by an trained psychologist. A mail preventing the subject of the call will be addressed approximately 10 days before. During the evaluations at the 6th month and 13th month, the number of suicidal repetitions will be reported, consumption of care since inclusion will be noted, the scale of suicidal ideation of Beck assessed, and a psychopathological evaluation carried out (Mini International Neuropsychiatric Interview DSM IV).

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 1040 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Supportive Care
Official Title: Effectiveness of a "Case Management Algorithm" After a Suicide Attempt in Terms of Repetition of the Suicidal Behaviors and Medico-economic Impact
Study Start Date : February 2010
Actual Primary Completion Date : July 2014
Actual Study Completion Date : July 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Suicide

Arm Intervention/treatment
Experimental: ALGOS group
Algorithm of case management over the 6 months following the suicidal gesture (systematic telephone contact, postcards and crisis card)
Behavioral: ALGOS algorithm of case management

If the subject survives one 1st SA (first attempter): he leaves the center where he was included with a "chart resource" (crisis card) which contains addresses of the Web sites of associations of prevention of the suicide, as well as an accessible phone number 24/24h.

If the subject is not a first attempter : he will be recontacted on the telephone between the 10th and the 21st day following the SA. If the subject is not contacted or little observing in the plan of care, it will receive a series of postcards then regularly, with 4 recoveries: to 2, 3, 4 and 5 months after the attempt.

Other Name: ALGOS Group

No Intervention: Control group
Treatment as usual (referral back to the general practitioner)

Primary Outcome Measures :
  1. Number of suicide re-attempters [ Time Frame: six months ]
    the number of suicide re-attempters 6 months following the attempt index

Secondary Outcome Measures :
  1. Number of deaths per suicide [ Time Frame: six months and 13 months ]
    Number of suicide re-attempts in the 6 months following the attempt index

  2. Number of lost to follow up [ Time Frame: six months and 13 months ]
  3. Number of suicide re-attempters [ Time Frame: 13 months ]
  4. Number of suicide re-attempts [ Time Frame: six months and 13 months ]
    Number of suicide re-attempts in the 6 months following the attempt index

  5. Suicidal ideation intensity [ Time Frame: six months and 13 months ]
    The suicidal ideation will be measured by Scale of Suicidal Ideation (A. Beck, M. Kovacs, and A. Weissman, 1979) in the 6 months following the attempt index and in the 13 months.

  6. medical cost [ Time Frame: six months and one year ]
    Numbers of hospitalisations, numbers of consultations, and drugs consummation during the year following the suicide attempt will be measured to estimate the medical cost

  7. Evaluation of the psychopathological profile [ Time Frame: six months and 13 months ]
    The psychopathological profile will be evaluated by the French version of Mini International Neuropsychiatric Interview (DSM IV)

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Surviving to a suicide attempt (SA) directly leaving the Emergency unit or have been hospitalized less than 7 days

Exclusion Criteria:

  • recidivists who made 4 SA and more in the 3 past years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01123174

Show Show 23 study locations
Sponsors and Collaborators
University Hospital, Lille
Layout table for investigator information
Principal Investigator: Guillauma VAIVA University Hospital, Lille
Principal Investigator: Michel WALTER University Hospital, Brest
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information
Responsible Party: University Hospital, Lille Identifier: NCT01123174    
Other Study ID Numbers: 2009_25
PHRC 2009/1902 ( Other Identifier: DHOS )
2009-A00893-54 ( Other Identifier: ID-RCB number, ANSM )
First Posted: May 14, 2010    Key Record Dates
Last Update Posted: June 18, 2015
Last Verified: June 2015
Keywords provided by University Hospital, Lille:
case management algorithm
suicidal behaviors
prevention of suicide
Additional relevant MeSH terms:
Layout table for MeSH terms
Suicide, Attempted
Self-Injurious Behavior
Behavioral Symptoms