Primary Outcome Measures:
- Development of meningitis [ Time Frame: within 4 weeks after neurosurgical operation ]
Secondary Outcome Measures:
- All-cause mortality [ Time Frame: within 4 weeks after the diagnosis of meningitis ]
Besides description of characteristics of patients with postneurosurgical patients, we also will investigate the usefulness of prolonged cerebrospinal fluid (CSF) culture, and profiles of blood and CSF inflammatory markers for the differential diagnosis of meningitis. CSF culture will be extended upto 2 weeks. Serum procalcitonin and C-reactive protein, CSF adenosine deaminase levels will be monitored and analyzed for the differential diagnosis of meningitis.