Childhood Cancer Survivor Study
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|ClinicalTrials.gov Identifier: NCT01120353|
Recruitment Status : Active, not recruiting
First Posted : May 10, 2010
Last Update Posted : June 26, 2020
|Condition or disease|
The study will focus on the following objectives:
- Characterize survivors' health with respect to disease- and treatment-related factors.
- Investigate the consequences of various intensities of exposure to chemotherapy and/or radiation on health outcomes (e.g., cardiovascular, reproductive, second cancers, etc…).
- Compare the mortality experience of survivors with the general population.
- Characterize the health-related behaviors, patterns of medical care, and medical follow-up needs of survivors.
- Describe patterns of familial aggregation of cancer, including known (and variations of) cancer family syndromes.
- Collect and store biologic samples (saliva, blood, second tumor tissue) to correlate with health outcomes and use for future research.
|Study Type :||Observational|
|Estimated Enrollment :||50000 participants|
|Official Title:||Childhood Cancer Survivor Study|
|Actual Study Start Date :||January 5, 1995|
|Estimated Primary Completion Date :||November 2021|
|Estimated Study Completion Date :||November 2021|
Survivors of cancer, diagnosed under 21 years of age, between 1970 and 1999 This project will study children and young adults exposed to specific therapeutic modalities, including radiation, chemotherapy, and/or surgery, for an increased risk of late-occurring events associated with excess mortality and morbidity.
A group of sibling controls will be identified to provide: (1) the ability to make direct comparisons with the survivors, (2) data on outcomes in a non-cancer population, and (3) additional comparison group to determine consistency of findings between data sources.
- To characterize survivors' health outcomes with respect to disease-, treatment, and genetic-related factors. [ Time Frame: 25 years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01120353
|Principal Investigator:||Gregory T. Armstrong, MD, MSCE||St. Jude Children's Research Hospital|