Try the modernized beta website. Learn more about the modernization effort.
Working… Menu

Cardiovascular Diseases in HIV-infected Subjects (HIV-HEART Study)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01119729
Recruitment Status : Completed
First Posted : May 10, 2010
Last Update Posted : May 10, 2010
Federal Ministry of Education and Reserach (BMBF)
Information provided by:
University Hospital, Essen

Brief Summary:
Human immunodeficiency virus (HIV) infection has been associated with a variety of cardiovascular diseases. Even most industrialised countries exhibit a growing and aging population of HIV-infected patients in the majority treated with antiretroviral drugs, the investigators still do not know much about the impact of cardiovascular diseases in this group of patients. The present study is an ongoing trial that was conducted as a prospective and multicentre survey, being schemed to analyse the frequency and clinical course of cardiac disorders in HIV-infected patients.

Condition or disease
Detection of Frequency, Severity and Progression of Cardiovascular Diseases in Patients With HIV-infection. Effect on Cardiovascular Risk and Life Quality by Age, Gender, Classic Cardiovascular Risk Factors, HIV-specific Cardiovascular Risk Factors, Cardiovascular Medication, Antiretroviral Medication

Layout table for study information
Study Type : Observational
Actual Enrollment : 803 participants
Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by the National Library of Medicine

MedlinePlus related topics: HIV/AIDS

HIV-infected Outpatients

Primary Outcome Measures :
  1. Prevalence of cardiovascular diseases
    Prevalence of cardiovascular diseases including coronary artery disease, congestive heart failure, peripheral arterial disease, cerebrovascular events, and valvular diseases.

Secondary Outcome Measures :
  1. Prevalence of cardiovascular disorders
    Prevalence of cardiovascular disorders determined by electrocardiography, exercise testing, echocardiography, blood samples.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
The study population included outpatients who were at least 18 years of age, had a known HIV-infection and exhibited a stable disease status within 4 weeks before inclusion of the trial. Patients were recruited during a 20-month period in a consecutive manner from September 2004 to May 2006. Written informed consent was obtained from all participants

Inclusion Criteria:

  • Age > 18 years
  • Known HIV-infection
  • Outpatients
  • Written informed consent

Exclusion Criteria:

● Acute cardiovascular disease or unstable hemodynamic status in the three weeks before inclusion

• Pregnancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01119729

Layout table for location information
Department of Dermatology, University Hospital of Bochum
Bochum, NRW, Germany, 44791
HIV Outpatient Department
Dortmund, NRW, Germany, 44137
HIV Outpatients Department
Duisburg, NRW, Germany, 47055
HIV Outpatient Department
Duisburg, NRW, Germany, 47259
Department of Dermatology, University Hospital of Essen
Essen, NRW, Germany, 45122
West German Heart Center Essen
Essen, NRW, Germany, 45122
HIV Outpatient Department
Essen, NRW, Germany, 45127
Sponsors and Collaborators
University Hospital, Essen
Federal Ministry of Education and Reserach (BMBF)
Publications of Results:
Other Publications:
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information
Responsible Party: PD Dr. med. Till Neumann, FESC, Competence Network of Heart Failure Identifier: NCT01119729    
Other Study ID Numbers: FKZ 01GI0205
First Posted: May 10, 2010    Key Record Dates
Last Update Posted: May 10, 2010
Last Verified: May 2010
Keywords provided by University Hospital, Essen:
Cardiac Diseases • HIV-Infection • AIDS • Antiretroviral Therapy
Additional relevant MeSH terms:
Layout table for MeSH terms
HIV Infections
Cardiovascular Diseases
Blood-Borne Infections
Communicable Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Immunologic Deficiency Syndromes
Immune System Diseases